Protein Alignment DNApol-theta and obe

DIOPT Version :9

• Sequence 1: NP_524333.1
• Gene: DNApol-theta / 41571
• FlyBaseID: FBgn0002905
• Length: 2059
• Species: Drosophila melanogaster
• Sequence 2: NP_650472.2
• Gene: obe / 41891
• FlyBaseID: FBgn0038344
• Length: 2183
• Species: Drosophila melanogaster
• Alignment Length: 1091
• Identity: 219/1091 - (20%)
• Similarity: 394/1091 - (36%)
• Gaps: 316/1091 - (28%)

  Fly    22 QADDKENA----QPGNGNIQVQSAGNEVNSEIQEINSEFFRDEFSYEVNQAHKPAEQSVVNVSQV 82
            :.|:.:||    :|..|:   ::...:||..||...|..:...||...:.::     ...|:.::
  Fly  1043 ELDELKNAYCKIKPYGGS---ENVHGKVNILIQTYLSNGYVKSFSLSSDMSY-----ITTNIGRI 1099

  Fly    83 QQHM-AVVSNQDSEDQSRSSALNDQICTQSSFEGEDAGADAVLDQ-PNLD--------------- 130
            .:.: ::|..|::...|.:..   |:|  ..||......|..|.| |.::
  Fly  1100 SRALFSIVLRQNNAVLSGNML---QLC--KMFERRQWDFDCHLKQFPTINAETIDKLERRGLSVY 1159

  Fly   131 ---------------ENSFL---------CPAQDEEASEQ--------LKEDILHSHS----VLA 159
                           .|::.         .|..:.|||.|        :|.||..|.:    |..
  Fly  1160 RLRDMEHRELKEWLRSNTYADLVIRSAHELPLLEVEASLQPITRTVLRIKVDIWPSFTWNDRVHG 1224

  Fly   160 K--QEF-------------YQEISQVTQNLSSMSPNQLRVSPNSSRIREAMPERPAMPLDLNTLR 209
            |  |.|             :.|:.|||:        :|.:|..|.::...:|.:..:|.......
  Fly  1225 KTCQSFWLWIEDPESNYIYHSELFQVTR--------KLVMSGQSQQLVMTIPLKEPLPPQYYIRV 1281

  Fly   210 SISAW-----NLPMSIQ----AEYKK--KGVVDMFDWQVECLSKPRLLFE--------------- 248
            |...|     .:|:|.|    .|:..  ..::.:....|.||.  .:::|
  Fly  1282 SSDNWLGSTTCIPLSFQHLVLPEHHPPLTELLPLRPLPVSCLK--NVVYESLYKFTHFNPIQTQI 1344

  Fly   249 -HC------NLVYSAPTSAGKTLVSEILMLKTVLERGK-KVLLILPFISVVREKM------FYMQ 299
             ||      |::..|||.:|||:|:||.:.:.:.:..| ||:.|.|..::|:|::      |...
  Fly  1345 FHCLYHTDNNVLLGAPTGSGKTIVAEIAIFRALNQNPKCKVVYIAPLKALVKERIADWEQRFQRS 1409

  Fly   300 DLLTPAGYRVEGFYGGYTPP-GGFESLHVAICTIEKANSIVNKLMEQGKLETIGMVVVDEVHLIS 363
            .|    |.:|....|..||. .......:.:.|.||.:.|......:..::.:.::|:||:||:.
  Fly  1410 SL----GLKVVELTGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREYVQHVSLIVIDEIHLLG 1470

  Fly   364 DKGRGYILELLLAKILYMSRRNGLQIQVITMSATLENVQLLQSWLDA-ELYITNYRPVALKEMIK 427
            : .||.::|:::::..::|...|..|:::.:|..|.|.|.|.:||.. ::.:.|::|
  Fly  1471 E-DRGPVIEVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGINKMGLYNFKP-------- 1526

  Fly   428 VGTVIYDHRLKLVRDVAKQKVLLKGLENDSDDVALLCIETLLEGCSVIVFCPSKDWCENLAVQ-- 490
                       .||.|..| |.:.|.                         |.|.:|..:|..
  Fly  1527 -----------SVRPVPLQ-VHINGF-------------------------PGKHYCPRMATMNR 1554

  Fly   491 -LATAIHVQIKSETVL---GQRLRTNL-------------NPRAIAEVKQQLRDIPTGLDGVMSK 538
             ...||......|..:   ..|.:|.|             ||:....:.:.  :|...|..:..:
  Fly  1555 PTFQAIRTYSPCEPTIVFVSSRRQTRLTALDLITFVAGESNPKQFLHIPED--EIELILQNIREQ 1617

  Fly   539 AITYACAF----HHAGLTTEERDIIEASFKAGALKVLVATSTLSSGVNLPARRVLIR-SPLFGGK 598
            .:.:..||    |||||..::|..:|..|....:::||||:||:.||||||..|:|: :..|.||
  Fly  1618 NLKFCLAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVATATLAWGVNLPAHLVVIKGTEYFDGK 1682

  Fly   599 -----QMSSLTYRQMIGRAGRMGKDTLGESILICNEINARMGRDLVVSELQPITSCLDMDGSTHL 658
                 .|......||:|||||...|..|.::::.::......:..:.... |:.|.|......|:
  Fly  1683 VKKYVDMPITDVLQMMGRAGRPQFDNEGVAVVLVHDEKKNFYKKFLYDPF-PVESSLLGVLPEHI 1746

  Fly   659 KRALLEVISSGVANTKEDIDF----FVNCTLLSAQKAFHAKEKPPDEESDANYINDALDFLVEYE 719
            .   .|:::..|.:.:..:|:    :....||.....:..::..|:.      :|:.:..||
  Fly  1747 N---AEIVAGTVQSKQAALDYLTWTYFFRRLLRNPSYYQLQDIEPEN------VNNFMSNLV--- 1799

  Fly   720 FVRLQRNEERETAVYVATRLGAACLASSMPPTDGLILFAELQKSRRSFVLESELHAVYLVTPYSV 784
                      |..||..:  .||||..    .||.::...|.:               :.:.|.:
  Fly  1800 ----------ERVVYELS--AAACLVE----RDGCLIPTFLGR---------------ISSYYYL 1833

  Fly   785 CYQLQDIDWLLYVHMWEKLSSPMKKVGELVGVRDAFLYKAL--RGQTKLDYKQMQIHKRF----- 842
            .|:...       |..|.|...|.....|:.:.|::.:..|  |.......::|....||
  Fly  1834 SYRTMK-------HFLEDLQPGMNTKKVLLAIADSYEFDQLPVRHNEDKHNEEMAEVSRFRPPSS 1891

  Fly   843 --------------------------YIALALEELVNETPINVVVHKYKCHRGMLQSLQQMASTF 881
                                      |:......|.|.|.:...:..|...||.|.:...:....
  Fly  1892 SWDSSYTKTFLLLQAHFARQSLPNSDYLTDTKSALDNATRVMQAMVDYTAERGWLSTTLVVQQLM 1956

  Fly   882 AGIVTAFCNSLQW---STLALIVSQFKDRL--FFGIHRDLIDLMRIPDLSQ 927
            ..::.|     :|   |....:....:|.|  |..|..|..|.:.:|.|.:
  Fly  1957 QSVIQA-----RWFDGSEFLTLPGVNEDNLDAFLNIPHDDYDYLTLPVLKE 2002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-theta	NP_524333.1	BRR2	209..978	CDD:224125	172/832 (21%)
		DEAD	251..404	CDD:278688	43/160 (27%)
		HELICc	542..616	CDD:197757	35/83 (42%)
		PolA	1489..2055	CDD:223820
		DNA_pol_A_theta	1668..2053	CDD:176475
obe	NP_650472.2	BRR2	450..1254	CDD:224125	42/231 (18%)
		DEAD	488..666	CDD:278688
		HELICc	790..866	CDD:197757
		Sec63	989..1296	CDD:280962	50/273 (18%)
		DEXDc	1332..1532	CDD:214692	52/223 (23%)
		DEAD	1338..1510	CDD:278688	45/176 (26%)
		HELICc	1605..1704	CDD:197757	36/100 (36%)
		SEC63	1818..2176	CDD:214744	33/212 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466312
Domainoid	1	1.000	45	1.000	Domainoid score	I721
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840