|
Fly 211 ISAWNLPMSIQAEYKKKGVVDMFDWQVECLSKPRLLFEHCNLVYSAPTSAGKTLVSEILMLKTVL 275
::.|.||.::..:|...||..||:||.|||...::| |..|||||||||||||||:|:|:||.||
Rat 72 LANWGLPKAVLEKYHNFGVKKMFEWQAECLLLGQVL-EGKNLVYSAPTSAGKTLVAELLILKRVL 135
Fly 276 ERGKKVLLILPFISVVREKMFYMQDLLTPAGYRVEGFYGGYTPPGGFESLHVAICTIEKANSIVN 340
|..||.|.||||:||.:||.:|:|.|....|.:|:|:.|..:|.|.|.||.||:||||:||.::|
Rat 136 ETRKKALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPTGRFSSLDVAVCTIERANGLIN 200
Fly 341 KLMEQGKLETIGMVVVDEVHLISDKGRGYILELLLAKILYMSRRN-----------GLQIQVITM 394
:|:|:.|::.:|.|||||:|::.|..|||:|||||.|:.:::|:: ...:|::.|
Rat 201 RLIEENKMDLLGTVVVDELHMLGDSHRGYLLELLLTKVCFVTRKSASCQADSASALACAVQIVGM 265
Fly 395 SATLENVQLLQSWLDAELYITNYRPVALKEMIKVGTVIYDHRLKLVRDVAKQKVL-LKGLENDSD 458
||||.|:||:.|||:||||.|::|||.|.|.||||..|||..:||||:. |.:| :|| |.|
Rat 266 SATLPNLQLVASWLNAELYHTDFRPVPLLESIKVGNSIYDSSMKLVREF--QPLLQVKG---DED 325
Fly 459 DVALLCIETLLEGCSVIVFCPSKDWCENLAVQLATA---IHVQ----IKSE----TVLGQRLRTN 512
.:..||.||:.:..||:||||||.|||.:|..:|.. :|.| :||. .:|.|
Rat 326 HIVSLCYETVRDNHSVLVFCPSKKWCEKVADIIAREFYNLHHQPEGLVKSSEFPPVILDQ----- 385
Fly 513 LNPRAIAEVKQQLRDIPTGLDGVMSKAITYACAFHHAGLTTEERDIIEASFKAGALKVLVATSTL 577
:::.||..||:..|:|||.|:...:.:..||||||||.|||||||.:|:.|.::||.|||||
Rat 386 ---KSLLEVIDQLKRSPSGLDSVLKNTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTL 447
Fly 578 SSGVNLPARRVLIRSPLFGGKQMSSLTYRQMIGRAGRMGKDTLGESILICNEINARMGRDLVVSE 642
|||||||||||:||:|:|||:.:..|||:||:|||||.|.||:|||||:|.......|..|:...
Rat 448 SSGVNLPARRVIIRTPVFGGQPLDILTYKQMVGRAGRKGVDTMGESILVCKNSEKSKGIALLQGS 512
Fly 643 LQPITSCLDMDG--STHLKRALLEVISSGVANTKEDIDFFVNCTLLSAQKAFHAKE-----KPPD 700
|:|:.|||...| ::.:.||:||:|.||||:|.:|:..:..||.|:|. .|| :...
Rat 513 LEPVHSCLQSQGEVTSTMIRAILEIIVSGVASTSQDMQTYAACTFLAAD----VKEGKQGIQRNR 573
Fly 701 EESDANYINDALDFLVEYEFVR-LQRNEERETAVYVATRLGAACLASSMPPTDGLILFAELQKSR 764
::.....::..:.:|:|.||:: .:.::.....||..|.||:|.|:||:.|||.|.:||:||::.
Rat 574 DDVQRGAVDACVTWLLENEFIQAAEPSDGTGGKVYHPTHLGSATLSSSLSPTDTLDIFADLQRAM 638
Fly 765 RSFVLESELHAVYLVTPYSVCYQLQDIDWLLYVHMWEKLSSPMKKVGELVGVRDAFLYKALRG-- 827
:.||||::||.|||||| |......|||..:..:||||.:.||:|.|||||.:.||.:.::|
Rat 639 KGFVLENDLHIVYLVTP--VFEDWTSIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKV 701
Fly 828 --QTKLDYKQMQIHKRFYIALALEELVNETPINVVVHKYKCHRGMLQSLQQMASTFAGIVTAFCN 890
:|:..::||.|||||:.:|.|.:|::|.|:..:..||.|:||.:|||||.|:.:||::|.|.|
Rat 702 VARTERQHRQMAIHKRFFTSLVLLDLISEIPLKEINQKYGCNRGQIQSLQQSAAVYAGMITVFSN 766
Fly 891 SLQWSTLALIVSQFKDRLFFGIHRDLIDLMRIPDLSQKRARALFDAGITSLVELAGADPVELEKV 955
.|.|..:.|::|||:.||.|||.|:|.||:|:..|:.:|||.|:.:|..::.:||.||.||:|..
Rat 767 RLGWHNMELLLSQFQKRLTFGIQRELCDLIRVSSLNAQRARFLYASGFLTVADLARADTVEVEAA 831
Fly 956 LYNSISFDSAKQHDHENADEAAKRNVVRNFYITGKAGMTVSEAAKLLIGEARQFVQHEIGLGTIK 1020
|.:::.|.||::...|..:.|.:|..:|..::.||: ::..|||.|::.||:..:|.::....::
Rat 832 LKDALPFKSARKAVDEEEEAAEERRSMRTIWVAGKS-LSAREAAALIVEEAKVILQQDLIEMGVQ 895
Fly 1021 WTQTQAGVEIASRAIHDGGEVDLHMSLEEEQPPVKRKLSIEENGT----ANSQKNPRLETVVD-- 1079
| ...:.:..::.::..|.||..|....:.:...||..|...|.. :|.:::|.....:|
Rat 896 W-GPHSPLSSSTHSLTSGSEVKEHTFKSQTKSSHKRLASKSRNSMRVSGSNGKQSPEAGQGLDEC 959
Fly 1080 -----------------TQRGYKVDKNIA---NQSKMNPNLKE---------------------- 1102
|...|:..|..: |:..:..:|||
Rat 960 RERPDSLCKFQGNHEIQTPSVYRARKRTSLGVNKEMLRTSLKEGKPSTKEVLQTLSFEKTRKAAL 1024
Fly 1103 ----IDAQN--------KARR---------NSTAHMDNL-------NPISNDP------------ 1127
..|.| |.|: :|..|.|:| :.:..||
Rat 1025 SFSSEQANNSFPSGRDRKYRKKSWGSSPMSDSVMHRDDLQGQTMCKSTLCEDPQKSLEEQNTEYR 1089
Fly 1128 -----------CQNNVNVKTAQP-----------------------IISNLNDIQ---------- 1148
|......||:.| :..|.|.::
Rat 1090 SPGLFAKNVSFCAKEKCNKTSFPLQMQQPCLRRKPESGAAVDHSVAVSQNKNVVEQPPGAPRDRR 1154
Fly 1149 ---------------KQGSQIEKMKINPATVVCSPQLANEEKPSTSQSARRKLVNEGMAERRRVA 1198
:.|::.:....:|. |..|.|..:..|:...|:|.:.||.|....|.
Rat 1155 GLAAHGRAEVNEVLTENGTESQLHDTHPV----SQCLENHSEKQTNTCTRQKTLTEGQAGISHVT 1215
Fly 1199 -----LMKIQ----QRTQKENQSKDQP---------IQASRS------------NQLSSP----- 1228
|..|: :...||:.|...| .:|.:| |.|:||
Rat 1216 RGSNDLTPIRCERLKLNSKEHDSNPCPQALGTNAGRTEAPQSSEALGQAGGQCENLLNSPGIQEK 1280
Fly 1229 -----VNRTP----ANRW-----------TQSE-----------------------------NPN 1244
.|:|. ||:. |||| .|:
Rat 1281 TSAHATNKTEHSHVANQAFCDFGDSLYLDTQSEEIIEQMATKNATQGAEAAGITEEGSATQNEPH 1345
Fly 1245 NEMNNSQLP-------------------------RRNPRN---QSPVPNANRTA----------- 1270
:......:| ||.|.: .||.|....:|
Rat 1346 STTGGQHIPGAANTDHVDRKNTESVKENPEKNIDRRTPHSLIFHSPTPQGGNSACFKENEHSVTD 1410
Fly 1271 -----------------------SRKVSNAEED------LFMAD---------DSFMLNTGL--- 1294
.|..:..||: |.|:| |||.....|
Rat 1411 SQLNSFLQGLETQDKPIIPLAPQMRTSTGVEEESLPETSLNMSDSILFDSFGEDSFGQRQSLDVK 1475
Fly 1295 --------------------------------------AAALTAAESKIAS-------------- 1307
..|..:.||.|.|
Rat 1476 AKQPLLSEMTPNHFHNPPYPQEDPVMTPHMSEPQGTLERMACLSGESIIFSEIDSAQVIEALDNM 1540
Fly 1308 ---------------------------CTEADVI------PSSQPKEPEV--IGALTPHASRLKR 1337
|.:.:|: .||:||..|: ..:.|..|:....
Rat 1541 AAFYMQENCNPITLKTEPRDLAALGNECPQGEVVRGEQHEGSSKPKFMEINQDNSFTWSAASFNL 1605
Fly 1338 SDQLRSQRIQSPSPTPQREIEIDLESKN----ESNGVSSMEISDMSM------------------ 1380
|.:| |||.....||:...|.:|...: |.|...|.|..||:.
Rat 1606 SPEL--QRILDKVSTPRENEEPELMHADLSCFEENSTESHERQDMNSDLGTVQRTSFLPSNGVKS 1668
Fly 1381 -------------------------ENPLMKNPLHLNASHIMSCSK------------------- 1401
:|.|:. |..|.||...|.||
Rat 1669 RTEGLESKAKHGGASSALPHKAAADDNGLIP-PTPLPASASASASKLALPEILGTSVKHQKASCL 1732
Fly 1402 ---------------------------VD--------------ETASSFSSIDIIDVCGHRNAFQ 1425
|| :.:.|..|:.||||...:..||
Rat 1733 FDSPSDNQNQDLSQELRDSLKDSDGSVVDTSFFLQSQDGLLLTQASCSSESLAIIDVASDQILFQ 1797
Fly 1426 AAIIEINNATRLGFSVG---LQAQAGKQKPLIGSNLLINQVAAAENREAAARERVLFQVDDTNF- 1486
..:.|.....|...|:. :.:....:...||..| .||.:.: ||: |:|..|
Rat 1798 TFVKEWQCQKRFSISLACEKMTSSTSSKTATIGGRL--KQVNSPQ--EAS--------VEDDGFP 1850
Fly 1487 --------ISGVSFCLADNVAYYWNMQIDERAAYQG---VPTPLKVQELCNLMARKDLTLVMHDG 1540
:.|::.|.....|||.::|.:::.:... .|.|| |.||.:.:.
Rat 1851 VHGSDCAVVVGLAVCWGGKDAYYLSLQKEQKQSEMSPSLAPPPL------------DATLTVKER 1903
Fly 1541 KEQLK-MLRKAIPQLKRI--------------------SAKLEDAKVANWLLQPD-KTVNFLNMC 1583
.|.|: .|:|...|.:.: ....||.|||.|||.|| |.....::.
Rat 1904 MEYLQSCLQKKSDQERSVVTYDFIQTYKVLLLSCGISLEPSYEDPKVACWLLDPDSKEPTLHSIV 1968
Fly 1584 QTFAPECTGLANLCGSGRGYSSYGLDTSSAILPRIRTAIESCVTLHILQG-----QTENLSRIGN 1643
.:|.|....|.....:|.|..|.||:.::....|.|.::||.:..:.:.. |.|||..|
Rat 1969 TSFLPHELALLEGIETGPGIQSLGLNVNTDHSGRYRASVESVLIFNSMNQLNSMLQKENLHDI-- 2031
Fly 1644 GDLLKFFHDIEMPIQLTLCQMEL--VGFPAQKQRLQQLYQRMVAVMKKVETKIYEQHGSRFNLGS 1706
|..:|||.|..|..:|| :||...:...|: ..|.|.:..:||:.|:..|..|:..|
Rat 2032 ------FCKVEMPSQYCLALLELNGIGFSTAECETQK--HIMQAKLDAIETQAYQLAGHSFSFTS 2088
Fly 1707 SQAVAKVLGLH--------------RKAKG----------------RVTTSRQVLEKLNS--PIS 1739
:..:|:||.|. ||..| |.:||:.:|.||.. |:.
Rat 2089 ADDIAQVLFLELKLPPNGEMKTQGGRKTLGSTRRGTESDRKLRLGRRFSTSKDILNKLKDLHPLP 2153
Fly 1740 HLILGYRKLSGLLAKSIQPLME------CCQADRIHGQSITYTATGRISMTEPNLQNVAKEFSIQ 1798
.|||.:|::|..:.|.:.||.. ..:.:||:..|.::||||||:.||||:|||.::|.|:
Rat 2154 GLILEWRRISNAITKVVFPLQREKHLNPFLRMERIYPVSQSHTATGRITFTEPNIQNVPRDFEIK 2218
Fly 1799 VGSDV-------------------------VH------------------ISCRSPFMPTDESRC 1820
:.:.| :| :|.|..|:|. ....
Rat 2219 MPTLVRESPPSQASGKGQLAMARQNQKVYGLHPGQRTVLEKTSDRGVPFSVSMRHAFVPF-PGGL 2282
Fly 1821 LLSADFCQLEMRILAHMSQDKALLEVMKSSQDLFIAIAAHWNKIEESEVTQDLRNSTKQVCYGIV 1885
:|:||:.|||:|||||:|:|..|::|:.|..|:|.:|||.|..||...|..:||...||:||||:
Rat 2283 ILAADYSQLELRILAHLSRDCRLIQVLNSGADVFRSIAAEWKMIEPDAVGDNLRQQAKQICYGII 2347
Fly 1886 YGMGMRSLAESLNCSEQEARMISDQFHQAYKGIRDYTTRVVNFARSKGFVETITGRRRYLENINS 1950
||||.:||.|.:...|.:|....|.|...||||..:....|...|..||||||.||||||..|..
Rat 2348 YGMGAKSLGEQMGIKENDAACYIDSFKSRYKGINHFMRDTVKNCRRDGFVETILGRRRYLPGIKD 2412
Fly 1951 DVEHLKNQAERQAVNSTIQGSAADIAKNAILKMEKNIERY---------REKLALGDNSVDL--- 2003
:..:.|..|||||:|:|:|||||||.|.|.:.::|.:|.: ||.:...|.:..|
Rat 2413 NNPYHKAHAERQAINTTVQGSAADIVKVATVNIQKQLETFHPTFKSHGHRESMLQSDRAGLLPKR 2477
Fly 2004 --------------VMHLHDELIFEVPTGKAKKIAKVLSLTMENCVKLSVPLKVKLRIGRSWGEF 2054
::.|||||::||......::|:::...||..:||||.||||::||.||||.
Rat 2478 KVKGMFCPMRGGFFILQLHDELLYEVAEEDVVQVAQIVKNEMECAIKLSVKLKVKVKIGASWGEL 2542
Fly 2055 KEVSV 2059
|:..|
Rat 2543 KDFDV 2547
| 
