Protein Alignment DNApol-theta and polg-1

DIOPT Version :9

• Sequence 1: NP_524333.1
• Gene: DNApol-theta / 41571
• FlyBaseID: FBgn0002905
• Length: 2059
• Species: Drosophila melanogaster
• Sequence 2: NP_496592.1
• Gene: polg-1 / 174860
• WormBaseID: WBGene00013258
• Length: 1072
• Species: Caenorhabditis elegans
• Alignment Length: 438
• Identity: 78/438 - (17%)
• Similarity: 141/438 - (32%)
• Gaps: 162/438 - (36%)

  Fly  1666 LVG--FPAQKQRLQQLYQRMVAVMKKVETKIYEQHGSRFNLGSSQAVAKVLGLHRKAKGRVTTSR 1728
            |||  ..:|:|.|..||                        |.:.| .|.|.|.::..|:...|.
 Worm   686 LVGADVDSQEQWLAALY------------------------GDASA-EKRLPLEKRVAGKTAFSN 725

  Fly  1729 QVL---EKLNSPISHLILGYRKLSGLLAKSIQPLMECCQADRIHGQSITY--------------- 1775
            .:|   :..|:.:..::....|:|...||.:       ...|::|...|:
 Worm   726 MMLAGSKSDNTDLHSVVASQLKISRNHAKVL-------NYARLYGSGETHAGKHLMRVGGLKQSE 783

  Fly  1776 ---TATGRISMTEPNLQNVAKEFSIQV---------------GSDVVHISCRSP--FMPTDESRC 1820
               ||:....:|:   .:|||...:.|               .|||..|.....  :||...|:
 Worm   784 AESTASQLFKLTK---GDVAKYMKVDVRMNCVVDKYIEEMVENSDVCKILTIDGIYYMPAYTSQ- 844

  Fly  1821 LLSADFCQLEMRILAHMSQ--------DKALLEVMKSSQD---LFIA--IAAHWNKIEESEVTQD 1872
             .:::..:.|..:|:|.|.        |..:..:.::..:   ||:.  .::.:|.:|.|....|
 Worm   845 -FASETVRFEDWLLSHYSSLLNGSSEPDSLIYSIYENPDEPRRLFVGGYESSTFNFLETSAAAHD 908

  Fly  1873 LRNSTKQVCYGIVYGMGMRSLAESLNCSEQEARMISDQFHQAYKGIRDYTTRVVNFARSKGFVET 1937
            ||...                   |.|      .|:|...:..:|
 Worm   909 LRTPI-------------------LGC------QIADSLGKLPEG-------------------- 928

  Fly  1938 ITGRRRYLENINSDVEHLKNQAERQAVNSTIQGSAADIAKNAILKMEKNIERYREKLALGDNSVD 2002
                       ..|..:...:.:|..:|..:|.||.|.....::.|:...:.|:         :|
 Worm   929 -----------TPDSAYFDRKYKRSVMNWIVQSSAVDFLHLLLVSMQWLCDTYK---------ID 973

  Fly  2003 --LVMHLHDELIFEVPTGKAKKIAKVLSLTMENCVKLSVPLKVKLRIG 2048
              .|:.:|||:.:......|.::|..|.|:     .|.|...:..|:|
 Worm   974 ARFVISIHDEVRYMCKEPDAPRLALALQLS-----NLLVRAYISQRVG 1016

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-theta	NP_524333.1	BRR2	209..978	CDD:224125
		DEAD	251..404	CDD:278688
		HELICc	542..616	CDD:197757
		PolA	1489..2055	CDD:223820	78/438 (18%)
		DNA_pol_A_theta	1668..2053	CDD:176475	76/436 (17%)
polg-1	NP_496592.1	DNApol_Exo	60..337	CDD:375581
		DNA_pol_A	605..1047	CDD:383059	78/438 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0749
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900