Protein Alignment PolQ and tam

DIOPT Version :10

• Sequence 1: NP_524333.1
• Gene: PolQ / 41571
• FlyBaseID: FBgn0002905
• Length: 2059
• Species: Drosophila melanogaster
• Sequence 2: XP_061513323.1
• Gene: tam / 1272128
• VectorBaseID: AGAMI1_013818
• Length: 1168
• Species: Anopheles gambiae
• Alignment Length: 1028
• Identity: 194/1028 - (18%)
• Similarity: 316/1028 - (30%)
• Gaps: 371/1028 - (36%)

  Fly  1150 QGSQIEKMKINPATVVCSPQLANEEKPSTSQSARRKLVNEGMAERRRVALMKIQQRTQKENQSKD 1214
            :|.::.:|.|.    :.|..|..:....|:|..|....:..:.:..|..|::
Mosquito    51 RGPRLNEMSIQ----MLSDSLYRQIFRPTAQHGRHAPASPTLVKSLRDDLLR------------- 98

  Fly  1215 QPIQASRSNQLSSPVNRTPANRWTQSENPNNEMNNSQL-PRRNPRNQSP--VPNANRTASR---- 1272
            ..|.||....|.....:.|..|....|...:.:...|. |.|....|.|  .||..:..||
Mosquito    99 HGIDASSPALLPDVDVKLPPLRGANIEEHFHSIAEEQSEPYRRAIEQLPGAPPNPPKVWSRTAGW 163

  Fly  1273 ----KVSNAEEDLFMADDSFML-----------------NTGLAAALTAAESKIASCTEADVIPS 1316
                .|:.:...:...||..::                 .||.|....:..|.:.|..||  .|:
Mosquito   164 TRYDPVTGSASSIPFPDDPALVFDVEVCVRAGPLPVMATATGTAGCWYSWTSPLLSSGEA--APT 226

  Fly  1317 SQPKEPEVIGALTPHASRLKRSDQLRSQRIQSPSPTPQREIEIDLESKNESNGVSSMEISDMSME 1381
            .|......:..|.|               :::.:||.:|                        :.
Mosquito   227 DQTAADYRLSQLIP---------------LEADTPTDER------------------------LH 252

  Fly  1382 NPLMKNPLHLNASH----IMSCSKVDETASSFSSIDIIDVC-GHRNAFQAAIIEINN---ATRLG 1438
            .|  :..:..|||:    :.....|:.||..|.....:.|| ....::|.|:::.:.   |...|
Mosquito   253 RP--RVVIGHNASYDRARVREQYWVEPTALRFLDTMSLHVCVSGITSYQRAMLKSSKQLPAEDAG 315

  Fly  1439 FSVGLQAQAGKQKPLIGSNLLINQVAAAENREAAARERVLFQVDDT------NFISGVSFCLAD- 1496
            :|        :|..|  :||.............|..:|..| |:.|      :|.|.:|:|.||
Mosquito   316 WS--------EQSSL--NNLADVYALYCGGPPLAKSQRDTF-VEGTLQDVRADFDSLMSYCAADV 369

  Fly  1497 ------------------------------NVAYY-----WNMQIDER-AAYQGVPTPLK----- 1520
                                          ..||.     |...:.|. .|::.:....|
Mosquito   370 RATGAVLQRLWPLFRERFPHPATLAGMLEMGSAYLPVNGNWTRYLTEADLAFEDLDLEAKHLLAQ 434

  Fly  1521 -VQELCNLM----ARKDLTLVMHDGKEQLKMLRKAIPQLKRISAKLE-------DAKVANWLLQP 1573
             .:..|.|:    .|:||.|...|.         ::.:||..:||:|       .:|....|...
Mosquito   435 RAEAACGLLHDAAYRRDLWLWDQDW---------SVQELKLKAAKVEGRKGKEPGSKAEEPLAGG 490

  Fly  1574 DKTVNFLN----------------------------MCQ--TFAPECTGLANLCGSGRGYSSYGL 1608
            |:....:|                            :|.  |....|.|     .||:      |
Mosquito   491 DEQTRLVNKFAHLYATASRLPVRRPLLPGYPAWYRALCSKPTAGDWCPG-----PSGK------L 544

  Fly  1609 DTSSAILPRIRTAIESCVTLHILQGQTENLSRIGNGDLL--KFFHDIEMPIQLTLCQMELVGFPA 1671
            .|...|.|::.:.......||.::|.       |.|.|:  |:..|.|              |.|
Mosquito   545 GTGMQIAPKLLSLCWEGYPLHYIRGH-------GWGFLVPFKYARDEE--------------FEA 588

  Fly  1672 QKQRLQQLYQRMVAVMKKVETKIYEQHGSRFNLGSSQAVAKVLGLH------------RKAKGRV 1724
            ....|.  .:::||....||.|    |.:.....|::|:|: |..|            |||....
Mosquito   589 DGAALP--LEQLVAACPVVEPK----HAAATPAESTEALAQ-LAKHVEQTISRKDYYRRKASDAS 646

  Fly  1725 TTSRQV----------LE----------------KLNSPISHLILGYRKLS-GLLA---KSIQPL 1759
            .|....          ||                ::.:|:|...|.  |.| .:||   ::.:.:
Mosquito   647 RTPAPYTGSGVWCNVELEGCCYFLKLPHKDGGGHRVGNPLSKDFLA--KFSENVLAGDGRAAERV 709

  Fly  1760 MECCQ--------ADRIHGQSITYTATGRISMTEPNLQNVAKEFSIQVGSDVVH-ISC----RSP 1811
            :|..:        .|||.||.:.:...|     ||:          .:|:.:.. :.|    |..
Mosquito   710 VEIARMLSYWRNNRDRIRGQLVVWCRPG-----EPD----------PIGAIIPQVVVCGTLTRRA 759

  Fly  1812 FMPTDESRCLLSADFCQLEMRILAHMSQDKALLEVMKSSQDLFIA-------IAAH------WNK 1863
            ..||..:......:....|:|.:........|:.....||:|:||       ...|      |..
Mosquito   760 MEPTWMTASNAQRERVGSELRAMVQAPPGYRLVGADVDSQELWIASVLGDAGTGLHGGTPFGWMT 824

  Fly  1864 IEESEVTQ-DLRNSTKQVC-----------YGIVYGMGMRSLAESLNCSEQEARMISDQFHQAYK 1916
            :..::.|: |:.:.|.|..           |..:||.|           :|.|..:..||:....
Mosquito   825 LSGTKATRTDMHSVTAQAVGISRDHAKVLNYARIYGAG-----------QQFAERLLKQFNPTLT 878

  Fly  1917 GIRDYTTRVVNFARSKGF-VETIT-GRRRYLENINSDVEHLKNQAERQAVNST 1967
            |..         ||||.. :.|:| |||.|...     |.|::|...|...||
Mosquito   879 GAE---------ARSKATKMFTLTKGRRTYRLR-----EELRDQYPTQPARST 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PolQ	NP_524333.1	BRR2	216..779	CDD:440817
		DNA_pol_A_theta	1668..2053	CDD:176475	80/382 (21%)
tam	XP_061513323.1	None