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Protein Alignment Past1 and EHD2

DIOPT Version :10

Sequence 1:	NP_731737.1	Gene:	Past1 / 41569	FlyBaseID:	FBgn0016693	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_055416.2	Gene:	EHD2 / 30846	HGNCID:	3243	Length:	543	Species:	Homo sapiens

Alignment Length:	541	Identity:	343/541 - (63%)
Similarity:	412/541 - (76%)	Gaps:	18/541 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SFLKR---EKNTQEVVENVIGELKKIYRSKLLPLEEHYQFHDFHSPKLEDPDFDAKPMILLVGQY 70
            |:|||   .....|.:..|...||::||:|||||||||:|..||||.|||.|||.|||:|:.|||
Human     3 SWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPMVLVAGQY 67

  Fly    71 STGKTTFIRYLLERDFPGIRIGPEPTTDRFIAVMYDDKEGVIPGNALVVDPKKQFRPLSKYGNAF 135
            |||||:||:||||::.||.|:|||||||.|:|||:.|.||.:|||||||||.|.||.|:.:||.|
Human    68 STGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDKPFRKLNPFGNTF 132

  Fly   136 LNRFQCSSVASPVLNAISIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDIS 200
            ||||.|:.:.:.||.:|||:||||||||.|||:.|||||..||.|||||||.||||||||||:||
Human   133 LNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEIS 197

  Fly   201 DEFRRSIEALKGHDDKIRIILNKADMIDHQQLMRVYGALMWSLGKVLQTPEVARVYIGSFWDQPL 265
            |||..:|.||:||:||||::||||||::.||||||||||||:||||:.||||.||||||||.|||
Human   198 DEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPL 262

  Fly   266 RFDANRRLFEDEEQDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAFIIAELRKDMPSVFGKDSK 330
            ....||||||.||||||||:|.|||:|||||||||:|||||.:|||:||:.|:|:|||||||::|
Human   263 LVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPSVFGKENK 327

  Fly   331 KKDLIKNLGQVYDRIQREHSISPGDFPDIKKMQEVLQHQDFTKFHSLKPHLLDIVDNMLAKDIAR 395
            ||.||..|..::.:||.||.||||||||.:||||:|...||||||||||.||:.:|.||..|||:
Human   328 KKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAK 392

  Fly   396 LMEMIPQEEM--TMVADPIVKGGAFEGVIDDHVSPFGYMKG------EGIDAGYGEHEWICNKDK 452
            ||.::.|||:  |.|.   |:||||||.   |:.|| ..:|      :|.:....|.||:..|||
Human   393 LMPLLRQEELESTEVG---VQGGAFEGT---HMGPF-VERGPDEAMEDGEEGSDDEAEWVVTKDK 450

  Fly   453 PRTDGIFNGLGPVDGKISGATAKQELIKSKLPNSVLSKIWKLSDVDGDGFLDSDEFALALHLINV 517
            .:.|.||..|.|.|||:||:.||..::.:|||||||.:||||||||.||.||.:|||||.|||..
Human   451 SKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEA 515

  Fly   518 KLEGCELPTVLPEHLVPPSKR 538
            ||||..||..||..|||||||
Human   516 KLEGHGLPANLPRRLVPPSKR 536

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.