Protein Alignment Arp1 and ACTL6A

DIOPT Version :10

• Sequence 1: NP_524331.2
• Gene: Arp1 / 41566
• FlyBaseID: FBgn0011745
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 139/420 - (33%)
• Similarity: 220/420 - (52%)
• Gaps: 63/420 - (15%)

  Fly    12 VVIDNGSGVIKAGFAGEHIPKCRFPNYIG----RPKHVRVMAGALEGD--------IFVGPKA-- 62
            :|.|.||..::||:|||..||..||..||    |.....:|  .::||        .::...|
Human    14 LVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLM--EIDGDKGKQGGPTYYIDTNALR 76

  Fly    63 --EEHRGLLSIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAA 125
              .|:...:|   |:::|:|.||:..:.|..:.| |..:.:....||||::|||.|.|..|||..
Human    77 VPRENMEAIS---PLKNGMVEDWDSFQAILDHTY-KMHVKSEASLHPVLMSEAPWNTRAKREKLT 137

  Fly   126 EFFFEGINAPALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDV 190
            |..||..|.||.|:...|||:.:|.||.||::||||...|.|:|:::|:.:...|::..:||..:
Human   138 ELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDSGATHTTAIPVHDGYVLQQGIVKSPLAGDFI 202

  Fly   191 TRYLKTLIR------------------REG--FNFRSTAEF-EIVRSIKEKVC------YLATNP 228
            |...:.|.:                  |||  .|::...:. ::.||....:|      :.|:..
Human   203 TMQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCVIQDFQASVL 267

  Fly   229 QKEETVETEKFA-------YKLPDGKIFEIGPARFRAPEVLFRPD----LLGEECEGIHDVLMYS 282
            |..::...|:.|       |:.|:|...:.|..|.:.||.||.|.    |.|....|:..|:..|
Human   268 QVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTMLGVSHVVTTS 332

  Fly   283 IEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIAAPQ---ERLYSTWMGG 344
            :...|:|:|..||.:::::||:||.:.|.|||..||.:.:...:::::.|..   ||.:|:|:||
Human   333 VGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVERRFSSWIGG 397

  Fly   345 SILASLDTFKKMWISKREYEEEGQKAVHRK 374
            ||||||.||::|||||:||||.|::.|.||
Human   398 SILASLGTFQQMWISKQEYEEGGKQCVERK 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	ASKHA_NBD_Arp1	9..375	CDD:466820	139/420 (33%)
ACTL6A	NP_004292.1	ASKHA_NBD_Arp4_ACTL6-like	8..420	CDD:466846	135/411 (33%)