Protein Alignment Arp1 and ACTL8

DIOPT Version :10

• Sequence 1: NP_524331.2
• Gene: Arp1 / 41566
• FlyBaseID: FBgn0011745
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_110439.2
• Gene: ACTL8 / 81569
• HGNCID: 24018
• Length: 366
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 117/378 - (30%)
• Similarity: 193/378 - (51%)
• Gaps: 45/378 - (11%)

  Fly    12 VVIDNGSGVIKAGFAGEHIPKCRFPNYIG------RPKHVRVMAGALEGDIFVGPKAEEHRGLLS 70
            |:||:|||.:|||.||.:.|:..|||.:.      .|                ||.....|..|.
Human     6 VIIDHGSGFLKAGTAGWNEPQMVFPNIVNYLPCKENP----------------GPSYARRRVSLG 54

  Fly    71 I--------RYPMEHGIVTDWNDMERIWSYI---YSKEQLATFTEDHPVLLTEAPLNPRRNREKA 124
            |        .||:|.|.:.:|..::.:||::   :.:||     |..||::||.||....:|:|.
Human    55 IDICHPDTFSYPIERGRILNWEGVQYLWSFVLENHRREQ-----EVPPVIITETPLREPADRKKM 114

  Fly   125 AEFFFEGINAPALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRD 189
            .|..||.::.|::.::.|..:||||:|.:||||:|||.|:|...|.::|..:|.|...::.||:|
Human   115 LEILFELLHVPSVLLADQLQMSLYASGLLTGVVVDSGYGLTRVQPFHQGRPLPASGKTLEFAGQD 179

  Fly   190 VTRYLKTLIRREGFNFRSTAEFEIVRSIKEKVCYLATN-------PQKEETVETEKFAYKLPDGK 247
            ::.||...:.:|..:.|...:.|.|...:...||:..|       .:::::...|...|:||||.
Human   180 LSAYLLKSLFKEDCDRRCLFQLETVAVTQMNKCYVPQNLGEALDFRERQQSALDESNTYQLPDGS 244

  Fly   248 IFEIGPARFRAPEVLFRPDLLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGD 312
            ..|:.|.:..|||:.|.|.:..:....|...::.|:|..::.||.:|..:::..||:||:.||..
Human   245 RVELTPMQRVAPEMFFSPQVFEQPGPSIPRAIVESVESCEISLRPLLVSHVMACGGNTLYPGFTK 309

  Fly   313 RLLSELKKHSAKDLKIRIAAPQERLYSTWMGGSILASLDTFKKMWISKREYEE 365
            ||..||........|..:.....|.:|.|:|.|::|.|.|::..|:|:.||.|
Human   310 RLFRELMGDHVSSTKATVWEGSNRNFSVWLGASVVAHLSTYQSEWMSREEYGE 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	ASKHA_NBD_Arp1	9..375	CDD:466820	117/378 (31%)
ACTL8	NP_110439.2	ACTIN	4..363	CDD:214592	117/378 (31%)