DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp1 and Actl9

DIOPT Version :9

Sequence 1:	NP_524331.2	Gene:	Arp1 / 41566	FlyBaseID:	FBgn0011745	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_899105.2	Gene:	Actl9 / 69481	MGIID:	1916731	Length:	415	Species:	Mus musculus

Alignment Length:	368	Identity:	138/368 - (37%)
Similarity:	215/368 - (58%)	Gaps:	6/368 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGLLSIRYPME 76
            ||||.|:|..|.||||:..|.......:|.....:......|.:.|:| :|...|..|.:..|:.
Mouse    51 VVIDMGTGTCKVGFAGQSQPTYTVATILGCQPKKQATKDQSELETFIG-EAARSRPELRLVKPIR 114

  Fly    77 HGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINAPALFVSM 141
            :|||.||...|.||.:|. :..|...|.:||:|.::.|.:|..||||..|..||.:::|||:|:.
Mouse   115 NGIVVDWEAAELIWRHIL-EHDLQVATHEHPLLFSDPPFSPATNREKLVEVAFESLHSPALYVAS 178

  Fly   142 QAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRREGFNFR 206
            |:|||:||.|||.|:|:|:|.||::.||:.:|:.:||:|.|:|:||..:|.:|..::...||:.:
Mouse   179 QSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQRLDLAGNHLTAFLAEMLLGSGFSLQ 243

  Fly   207 STAEFEIVRSIKEKVCYLATNPQKEETVETE--KFAYKLPDGKIFEIGPARFRAPEVLFR-PDLL 268
            . .:.::|.:||...||||.:.|||:....|  |.:.|||||:...:|...|:.||:||. |::.
Mouse   244 Q-EDLDLVENIKHHYCYLAPDFQKEQARPDEECKQSLKLPDGRTVTLGKELFQCPELLFHPPEIP 307

  Fly   269 GEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIAAP 333
            |....|:..:...|:.|...:||..:.:|::|.|||:||.|...|..:||....:.:..:.:.|.
Mouse   308 GLSPIGLPAMAEQSLLKVPQELRPHVARNVILCGGSSLFTGLEGRFRAELLHSLSPEDHVVVMAH 372

  Fly   334 QERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF 376
            ..|..|.|:||||||||..|:..|:.:.:|||.|.:.|:||.:
Mouse   373 PNRNLSVWIGGSILASLHAFQSCWVLREQYEERGPQVVYRKCY 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	NBD_sugar-kinase_HSP70_actin	5..376	CDD:302596	138/366 (38%)
Arp1	NP_524331.2	ACTIN	9..376	CDD:214592	138/366 (38%)
Actl9	NP_899105.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
Actl9	NP_899105.2	ACTIN	48..414	CDD:214592	137/365 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910