DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp1 and Actl9b

DIOPT Version :9

Sequence 1:	NP_524331.2	Gene:	Arp1 / 41566	FlyBaseID:	FBgn0011745	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001013915.1	Gene:	Actl9b / 292516	RGDID:	1359476	Length:	411	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	148/383 - (38%)
Similarity:	227/383 - (59%)	Gaps:	14/383 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EPYDVVVNQ------PVVIDNGSGVIKAGFAGEHIPKCRFPNYIG-RPKHVRVMAGALEGDIFVG 59
            ||..|..|:      .||||.|:|:.|.||||:..|.....|.:| :||. |......:.::|:|
  Rat    31 EPCGVFGNKGTTKMSGVVIDMGTGICKMGFAGQTRPTYIVRNIVGCQPKR-RTTMEQPKMEMFIG 94

  Fly    60 PKAEEHRGLLSIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKA 124
             :|...|..|::.:|:.:|||.||...|.||.:|...: |...|:|||:|.|:.|.||..||||.
  Rat    95 -EAAHARPELTLMHPVRNGIVVDWEAAEFIWRHILEND-LRLDTQDHPLLFTDPPFNPASNREKL 157

  Fly   125 AEFFFEGINAPALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRD 189
            .|..||.:::||::|:.|:|||:||.|||.|:|:|:|.||::.||:::|:.:|..|.|:|:||..
  Rat   158 VEVAFESLHSPAIYVASQSVLSVYANGRVNGLVVDTGHGVSYTVPVFQGYNLPSGIQRMDLAGHY 222

  Fly   190 VTRYLKTLIRREGFNFRSTAEFEIVRSIKEKVCYLATNPQKEETVETEKF--AYKLPDGKIFEIG 252
            :|::|...|.|..|..:. .:.:.:.:||::.||:|.:.|||:....|||  ..|||||::..:|
  Rat   223 LTKFLAEKILRSSFAVKK-EDMDTMENIKQQYCYVALDFQKEQGRPDEKFRRCLKLPDGQMITVG 286

  Fly   253 PARFRAPEVLFR-PDLLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLS 316
            ...|:.||:||. ||..|....|:..::.:|:.....:||..:.||::|.|||:||.||..|..:
  Rat   287 KELFQCPELLFHPPDTSGPSSLGLPSMVEHSLSTVPQELRADMEQNVLLCGGSSLFTGFEGRFKT 351

  Fly   317 ELKKHSAKDLKIRIAAPQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRK 374
            ||.:....:..:.:.|...|..|.|:||||||||..|:..|:.:.:|||.|...|.||
  Rat   352 ELLRRLGPEAHVVVVAQANRNLSVWIGGSILASLCAFQTRWVLREQYEEHGPDIVLRK 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	NBD_sugar-kinase_HSP70_actin	5..376	CDD:302596	146/380 (38%)
Arp1	NP_524331.2	ACTIN	9..376	CDD:214592	145/376 (39%)
Actl9b	NP_001013915.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		NBD_sugar-kinase_HSP70_actin	45..410	CDD:302596	144/369 (39%)
		Actin	47..411	CDD:278451	144/367 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910