DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp1 and arp-1

DIOPT Version :9

Sequence 1:	NP_524331.2	Gene:	Arp1 / 41566	FlyBaseID:	FBgn0011745	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_497108.2	Gene:	arp-1 / 175162	WormBaseID:	WBGene00013168	Length:	374	Species:	Caenorhabditis elegans

Alignment Length:	373	Identity:	244/373 - (65%)
Similarity:	297/373 - (79%)	Gaps:	1/373 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YDVVVNQPVVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGL 68
            |||:.||||||||||||||||||||..||.||.|::||||:.|||||.|:||||:|||||.:|||
Worm     3 YDVIANQPVVIDNGSGVIKAGFAGEQQPKVRFANFVGRPKYHRVMAGGLDGDIFIGPKAESNRGL 67

  Fly    69 LSIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGIN 133
            .||.||||||||.:|:|||:||.||:.::||..|.|:||||||:|||||.:|||::||.|||..|
Worm    68 FSIEYPMEHGIVNNWSDMEKIWEYIFGQDQLKIFPEEHPVLLTDAPLNPLKNRERSAEIFFETFN 132

  Fly   134 APALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLI 198
            .|||::.||||||||||||.|||||||||||||||||.:||||.|:|.|:|:||||||.||:.|:
Worm   133 VPALYIQMQAVLSLYATGRTTGVVLDSGDGVTHAVPIVKGFAMKHAIQRMDLAGRDVTEYLRVLL 197

  Fly   199 RREGFNFRSTAEFEIVRSIKEKVCYLATNPQKEETVETEKFAYKLPDGKIFEIGPARFRAPEVLF 263
            ||||:.|..:.||||||.:||..||||.:|.|.|. .:.|.:|.|||....||..:.||||||||
Worm   198 RREGYEFHRSNEFEIVREMKENACYLALDPTKVEN-NSVKSSYALPDTTKIEISNSLFRAPEVLF 261

  Fly   264 RPDLLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKI 328
            :|||:|.|..|:..|:..||.|.|:|||:.||.|||||||:|||||||||||.|::|.:..|.||
Worm   262 KPDLIGTEWPGMAHVVNQSIMKCDVDLRQTLYSNIVLSGGTTLFKGFGDRLLGEMRKIAPADGKI 326

  Fly   329 RIAAPQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF 376
            ||:|.|||...||:||||:||||||:|||:.|:|||:.|..|:|::.|
Worm   327 RISASQERNSLTWIGGSIVASLDTFRKMWLGKKEYEDMGASAMHKRFF 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	NBD_sugar-kinase_HSP70_actin	5..376	CDD:302596	242/370 (65%)
Arp1	NP_524331.2	ACTIN	9..376	CDD:214592	240/366 (66%)
arp-1	NP_497108.2	NBD_sugar-kinase_HSP70_actin	4..374	CDD:302596	242/370 (65%)
arp-1	NP_497108.2	ACTIN	8..374	CDD:214592	240/366 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166362
Domainoid	1	1.000	492	1.000	Domainoid score	I183
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21173
Inparanoid	1	1.050	502	1.000	Inparanoid score	I741
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55293
OrthoDB	1	1.010	-	-		D306902at33208
OrthoFinder	1	1.000	-	-		FOG0000057
OrthoInspector	1	1.000	-	-		oto18967
orthoMCL	1	0.900	-	-		OOG6_103845
Panther	1	1.100	-	-	LDO	PTHR11937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4323
SonicParanoid	1	1.000	-	-		X3841
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940