Protein Alignment Arp1 and ACTRT1

DIOPT Version :10

• Sequence 1: NP_524331.2
• Gene: Arp1 / 41566
• FlyBaseID: FBgn0011745
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_612146.1
• Gene: ACTRT1 / 139741
• HGNCID: 24027
• Length: 376
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 153/367 - (41%)
• Similarity: 228/367 - (62%)
• Gaps: 4/367 - (1%)

  Fly    12 VVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGLLSIRYPME 76
            |:.|||||:.|||.:||..|:....:.:|..| ..|....|....|||.:|......|.:.||:|
Human    12 VIFDNGSGLCKAGLSGEIGPRHVISSVLGHCK-FNVPLARLNQKYFVGQEALYKYEALHLHYPIE 75

  Fly    77 HGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINAPALFVSM 141
            .|:||.|:|||::|.:::.:| |.......|||:||..||||..|||.||..||..:.|..::|.
Human    76 RGLVTGWDDMEKLWKHLFERE-LGVKPSQQPVLMTEPSLNPREIREKLAEMMFETFSVPGFYLSN 139

  Fly   142 QAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRREGFNFR 206
            .||.:|||:..|||:|:|||||||..|||:||:::||::.::.:||||:|.:|..|:...||||.
Human   140 HAVAALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVTKLCMAGRDITEHLTRLLFASGFNFP 204

  Fly   207 STAEFEIVRSIKEKVCYLATNPQKEETVETEKF--AYKLPDGKIFEIGPARFRAPEVLFRPDLLG 269
            ......:|.:||||:||:|..|:||......:.  ||:||||.:...|...::.|||||.||.||
Human   205 CILNKAVVNNIKEKLCYIALEPEKELRKSRGEVLGAYRLPDGHVIHFGDELYQVPEVLFAPDQLG 269

  Fly   270 EECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIAAPQ 334
            ....|:..::..||.|.|.|::..||.:||||||:||..|..:||:.|:::.::|...|:|.|..
Human   270 IHSPGLSKMVSSSIMKCDTDIQNKLYADIVLSGGTTLLPGLEERLMKEVEQLASKGTPIKITASP 334

  Fly   335 ERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF 376
            :|.:|.|:|.||:.|:.:||:||::..:::|.|...|.|:.|
Human   335 DRCFSAWIGASIMTSMSSFKQMWVTSADFKEYGTSVVQRRCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	ASKHA_NBD_Arp1	9..375	CDD:466820	152/364 (42%)
ACTRT1	NP_612146.1	ASKHA_NBD_actin_Arp-T1-3	10..367	CDD:466848	149/356 (42%)