Protein Alignment Arp1 and ACTR1B

DIOPT Version :9

• Sequence 1: NP_524331.2
• Gene: Arp1 / 41566
• FlyBaseID: FBgn0011745
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005726.1
• Gene: ACTR1B / 10120
• HGNCID: 168
• Length: 376
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 290/376 - (77%)
• Similarity: 342/376 - (90%)
• Gaps: 0/376 - (0%)

  Fly     1 MEPYDVVVNQPVVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEH 65
            ||.||::.|||||||||||||||||||:.|||..||||:|||||:||||||||||:|:|||||||
Human     1 MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEH 65

  Fly    66 RGLLSIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFE 130
            ||||:||||||||:|.|||||||||.|:|||:||.||:|:||||||||||||.:|||||||.|||
Human    66 RGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFE 130

  Fly   131 GINAPALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLK 195
            ..|.||||:|||||||||||||.|||||||||||||||||||||||||||||||||||||:|||:
Human   131 TFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLR 195

  Fly   196 TLIRREGFNFRSTAEFEIVRSIKEKVCYLATNPQKEETVETEKFAYKLPDGKIFEIGPARFRAPE 260
            .|:|:||.:|.::||||:||:|||:.|||:.||||:|.:||||..|.||||...::|||||||||
Human   196 LLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPE 260

  Fly   261 VLFRPDLLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKD 325
            :||:|||:|:|.||:|:|:.::|.|||||||:.|:.|||||||||||||||||||||:||.:.||
Human   261 LLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKD 325

  Fly   326 LKIRIAAPQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF 376
            :||:|:||||||||||:|||||||||||||||:||:||||:|.:|:|||||
Human   326 IKIKISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	NBD_sugar-kinase_HSP70_actin	5..376	CDD:302596	285/370 (77%)
		ACTIN	9..376	CDD:214592	284/366 (78%)
ACTR1B	NP_005726.1	NBD_sugar-kinase_HSP70_actin	5..376	CDD:418402	285/370 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	619	1.000	Domainoid score	I180
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	635	1.000	Inparanoid score	I833
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55293
OrthoDB	1	1.010	-	-		D306902at33208
OrthoFinder	1	1.000	-	-		FOG0000057
OrthoInspector	1	1.000	-	-		otm41852
orthoMCL	1	0.900	-	-		OOG6_103845
Panther	1	1.100	-	-	O	PTHR11937
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4323
SonicParanoid	1	1.000	-	-		X3841
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870