Protein Alignment Arp1 and POTEB

DIOPT Version :9

• Sequence 1: NP_524331.2
• Gene: Arp1 / 41566
• FlyBaseID: FBgn0011745
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001264233.1
• Gene: POTEB / 100996331
• HGNCID: 33734
• Length: 544
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 72/432 - (16%)
• Similarity: 128/432 - (29%)
• Gaps: 163/432 - (37%)

  Fly    17 GSGVIKAGFAGEH-------------------IPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKA 62
            |||....|.:|:|                   .|.||     |..|......|..:...|:.|:.
Human    37 GSGTSNVGTSGDHDDSFMKTLRSKMGKWCCHCFPCCR-----GSGKSNVGTWGDYDDSAFMEPRY 96

  Fly    63 EEHRGLLSIRYPMEHGIVTDWNDMERI-----WSYIYSKEQLATFTEDHPVLLTEAPLNPRRNRE 122
            ...|                 .|::::     |..:..|:.:        |:|.:..:| :|:::
Human    97 HVRR-----------------EDLDKLHRAAWWGKVPRKDLI--------VMLRDTDMN-KRDKQ 135

  Fly   123 KAAEFFFEGINAPALFVSM----------------------------QAVLSLYATGRVTGVVLD 159
            |.........|..:..|.:                            :.||.|...|....:..:
Human   136 KRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDE 200

  Fly   160 SGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRREGFNFRSTAEFEIVRSIKEKVC-- 222
            .|:...|.....|...|..:::   :.|.|:                         ..|.| |
Human   201 YGNTALHYAIYNEDKLMAKALL---LYGADI-------------------------ESKNK-CGL 236

  Fly   223 ---YLATNPQKEETVETEKFAYKLPDGKIFEIGPARFRAPEVLFRPDLLGEECEG----IHDVLM 280
               .|..:.||:|.|   ||..|         ..|...|.:...|..|:...|.|    ::.:|.
Human   237 TPLLLGVHEQKQEVV---KFLIK---------KKANLNALDRYGRTALILAVCCGSASIVNLLLE 289

  Fly   281 YSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIAAPQERLYSTWMGGS 345
            .:::.|..||.....:...:|....:.    ..|||:.|:.....:....:.|::.|.
Human   290 QNVDVSSQDLSGQTAREYAVSSHHHVI----CELLSDYKEKQMLKISSENSNPEQDLK------- 343

  Fly   346 ILASLDTFKKMWISK------------------REYEEEGQK 369
             |.|.:..:::.:|:                  ||.|||.:|
Human   344 -LTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKK 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	NBD_sugar-kinase_HSP70_actin	5..376	CDD:302596	72/432 (17%)
		ACTIN	9..376	CDD:214592	72/432 (17%)
POTEB	NP_001264233.1	ANK	130..255	CDD:238125	25/157 (16%)
		ANK 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00023	135..167		3/31 (10%)
		ANK repeat	137..166	CDD:293786	2/28 (7%)
		ANK 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00023	168..200		4/31 (13%)
		ANK repeat	168..199	CDD:293786	4/30 (13%)
		ANK	196..320	CDD:238125	28/168 (17%)
		ANK 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00023	201..233		7/59 (12%)
		ANK repeat	201..232	CDD:293786	6/58 (10%)
		ANK 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00023	234..266		11/43 (26%)
		ANK repeat	234..265	CDD:293786	11/42 (26%)
		ANK 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00023	267..299		6/31 (19%)
		ANK repeat	267..298	CDD:293786	6/30 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	332..457		11/61 (18%)
		SMC_N	<412..>542	CDD:330553
		CCDC144C	489..>542	CDD:317340

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900