Protein Alignment Arp1 and ACTR3

DIOPT Version :9

• Sequence 1: NP_524331.2
• Gene: Arp1 / 41566
• FlyBaseID: FBgn0011745
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005712.1
• Gene: ACTR3 / 10096
• HGNCID: 170
• Length: 418
• Species: Homo sapiens
• Alignment Length: 406
• Identity: 136/406 - (33%)
• Similarity: 207/406 - (50%)
• Gaps: 61/406 - (15%)

  Fly    13 VIDNGSGVIKAGFAGEHIPKCRFPNYI--------GRPKHVRVMAGALEGDIFVGPKAEEHRGLL 69
            |:|.|:|..|.|:||...|:...|:.|        |.....|||.|..:.|.|:|.:|.| :...
Human     9 VVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEAIE-KPTY 72

  Fly    70 SIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINA 134
            :.::|:.||||.||:.|||....:..| .|....|||..||||.|||...|||..||..||..|.
Human    73 ATKWPIRHGIVEDWDLMERFMEQVIFK-YLRAEPEDHYFLLTEPPLNTPENREYTAEIMFESFNV 136

  Fly   135 PALFVSMQAVLSLYA--TGR------VTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVT 191
            |.|::::||||:|.|  |.|      :||.|:||||||||.:|:.||:.:...|..:.|||||:|
Human   137 PGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDIT 201

  Fly   192 RYLKTLIRREGFNFRSTAEFEIVRSIKEKVCYLATNPQKE------------------ETVETEK 238
            .:::.|:|............|..:::||:..|:..:..||                  ..:..::
Human   202 YFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKE 266

  Fly   239 FAYKLPDGKIFEIGPARFRAPEVLFRPDLLGEE-CEGIHDVLMYSIEKSDMDLRKMLYQNIVLSG 302
            |:        .::|..||..||:.|.|:....: .:.|.:|:...|:...:|:|:.||:||||||
Human   267 FS--------IDVGYERFLGPEIFFHPEFANPDFTQPISEVVDEVIQNCPIDVRRPLYKNIVLSG 323

  Fly   303 GSTLFKGFGDRLLSELKKH----------------SAKDLKIRIAAPQERLYSTWMGGSILASLD 351
            |||:|:.||.||..:||:.                ..|.:.:::.....:.|:.|.|||:|||..
Human   324 GSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTP 388

  Fly   352 TFKKMWISKREYEEEG 367
            .|.::..:|::|||.|
Human   389 EFYQVCHTKKDYEEIG 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp1	NP_524331.2	NBD_sugar-kinase_HSP70_actin	5..376	CDD:302596	136/406 (33%)
		ACTIN	9..376	CDD:214592	136/406 (33%)
ACTR3	NP_005712.1	PTZ00280	2..417	CDD:240343	136/406 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910