Protein Alignment Cyp313a4 and CYP4F2

DIOPT Version :9

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001073.3
• Gene: CYP4F2 / 8529
• HGNCID: 2645
• Length: 520
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 124/500 - (24%)
• Similarity: 217/500 - (43%)
• Gaps: 70/500 - (14%)

  Fly     1 MLTWTLWCGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMAHWLMRREDILNAFGCFLDKHG 65
            :|....|.....|.|.|..:...|    .|:.     :|.....:|....:.::|.     .:.|
Human    23 LLVGASWLLAHVLAWTYAFYDNCR----RLRC-----FPQPPRRNWFWGHQGMVNP-----TEEG 73

  Fly    66 PTIFS------------WLGPI-PFMIVSDPQVVQDIFTSPHCV--NKGIIYKAVDDGAGVGLFS 115
            ..:.:            |:||| |.:.:..|.:::.:..:...:  .....|..::...|.||..
Human    74 MRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSFLEPWLGDGLLL 138

  Fly   116 LKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK--DLIPLLQSFTLGIA 178
            ....:||.||::|.|||...:|..::.|||....::..:.:.|..:|..  |:...:...||...
Human   139 SAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTLDSL 203

  Fly   179 TQTTMGSDVKDEES--------FRSNSLLG-RYQCILETMTDMCFSPWLNSRFCRQLAGKESHYY 234
            .:.....|...:|.        ...::|:. |:..||           |:..|...|......:.
Human   204 QKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL-----------LHIDFLYYLTPDGQRFR 257

  Fly   235 QAKTEIRQFIRKII-ERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVED------- 291
            :|...:..|...:| ||:......|....:|:..|:..|:.:      .|..|...||
Human   258 RACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFI------DVLLLSKDEDGKKLSDE 316

  Fly   292 ----ESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYL 352
                |::..:|...:|||:.:.:.|..||..||||||..:|::.:..:....::.:.|...:.:|
Human   317 DIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFL 381

  Fly   353 DLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHF 417
            .:.:.||:|:.|||||:||..:||:.|.:|.|:|||:...|.::..|.:..:| ||.|.::|..|
Human   382 TMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYDPFRF 445

  Fly   418 LPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYR 462
            .|.||:::.|.|:|||:.|.|||||..:|:...||.||..|..:|
Human   446 DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	p450	33..465	CDD:299894	116/467 (25%)
CYP4F2	NP_001073.3	DUF4175	4..>57	CDD:372724	8/42 (19%)
		p450	52..515	CDD:365848	116/461 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810