Protein Alignment Cyp313a4 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 485
• Identity: 128/485 - (26%)
• Similarity: 228/485 - (47%)
• Gaps: 57/485 - (11%)

  Fly     6 LWCGLLFLLWIYFLWSRRRFYLLTLK-IPGPLGYPILGMAHWLM-----RREDILNAFGCFLDKH 64
            ::|..|.|:....|:.||:..|..|. .|||       .||||:     .:||.:......:.||
Mouse    19 VFCLALVLMQAMKLYLRRQRLLRDLSPFPGP-------PAHWLLGHQKFLQEDNMETLDEIVKKH 76

  Fly    65 GPTIFSWLGPI-PFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLKDPRWSIHRKLL 128
            ......|:||. .|..:.||...: ||.|........:::.:....|.||.:|..|||..||.||
Mouse    77 PCAFPCWVGPFQAFFYIYDPDYAK-IFLSRTDPKMQYLHQLLTPCIGRGLLNLDGPRWFQHRCLL 140

  Fly   129 NPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK--DLIPLLQSFTLGIATQTTMGSDVKDEE 191
            .|||...:|...:........::||:.|.:....|.  ::...:...||.|..:...|.:...:
Mouse   141 TPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQ- 204

  Fly   192 SFRSNSLLGRYQCIL-------ETMTDMCFSPW--------LNSR-FCRQLAGKESHYYQAKTEI 240
                  :.|.|:..:       |.::...::.|        |:.: .|.|..||..|.|..|  |
Mouse   205 ------INGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQYTEK--I 261

  Fly   241 RQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRG--VFTLKNVEDESNIIVFGAFET 303
            .|..:||::.::.:|:        :....:||::|.......  .|:..::..|.|..::...:.
Mouse   262 IQDRKKILKNQVKQDD--------TQTSQIFLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDA 318

  Fly   304 TANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGD-FDVSYADTQQMVYLDLILNESMRVIPPVP 367
            :|.::.:.|..||:.||:|:|...||::|.   || ..:::....:|.|..:.:.|::|:|||||
Mouse   319 SAASISWLLYCLALNPEHQDRCRTEIRSIL---GDGSSITWEQLDEMSYTTMCIKETLRLIPPVP 380

  Fly   368 VVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKHPYAYIP 432
            .:||:.|:.|.|.:|..:|.|:.:.:.|:.:|.:..:|. |.:.|:|..|...|...:||.|::|
Mouse   381 SISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWN-DPKVFDPLRFTKENSDQRHPCAFLP 444

  Fly   433 FTKGIRNCIGWRYALISAKVTLAKLLRNYR 462
            |:.|.|||||.::|::..||.:|.:|.:::
Mouse   445 FSSGPRNCIGQQFAMLELKVAIALILLHFQ 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	109/420 (26%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	111/431 (26%)