Protein Alignment Cyp313a4 and CYP4F12

DIOPT Version :9

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_076433.3
• Gene: CYP4F12 / 66002
• HGNCID: 18857
• Length: 524
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 119/421 - (28%)
• Similarity: 201/421 - (47%)
• Gaps: 48/421 - (11%)

  Fly    71 WLGP-IPFMIVSDPQVVQDIFTSPHCV--NKGIIYKAVDDGAGVGLFSLKDPRWSIHRKLLNPAF 132
            |||| |||:::..|..::.|..:...:  ...:..:.:....|.|:......:||.||::|.|||
Human    91 WLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAF 155

  Fly   133 GHKVLLSFLPIFNRETALLLDQLEPLQDDGEK--DLIPLLQSFTLGIATQTTMGSDVKDEESFRS 195
            ...:|.|::.|||:...::||:.:.|..:|..  |:...:...||....:.....|...:|  |.
Human   156 HFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQE--RP 218

  Fly   196 NSLLG-----------RYQCILETMTDMCFSPWLNSRFCRQLAGKESHYYQAKTEIRQFIRKII- 248
            :..:.           |.|.||:.|.           |...|:.....:::|...:..|...:|
Human   219 SEYIATILELSALVEKRSQHILQHMD-----------FLYYLSHDGRRFHRACRLVHDFTDAVIR 272

  Fly   249 ERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVED-----------ESNIIVFGAFE 302
            ||:......|.....:...|:..|:.:      .|..|...||           |::..:||..:
Human   273 ERRRTLPTQGIDDFFKDKAKSKTLDFI------DVLLLSKDEDGKALSDEDIRAEADTFMFGGHD 331

  Fly   303 TTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVP 367
            |||:.:.:.|..||..||||||..:|::.:..:....::.:.|..|:.:|.:.:.||:|:.||.|
Human   332 TTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAP 396

  Fly   368 VVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKHPYAYIP 432
            .:||..:||:.|.:|.|:|||:...|||..:|.:..:| ||.|.::|..|.|.|.:.:.|.|:||
Human   397 FISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDPEVYDPFRFDPENSKGRSPLAFIP 460

  Fly   433 FTKGIRNCIGWRYALISAKVTLAKLLRNYRF 463
            |:.|.|||||..:|:...||.||.:|.::||
Human   461 FSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	p450	33..465	CDD:299894	119/421 (28%)
CYP4F12	NP_076433.3	p450	52..506	CDD:306555	119/421 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810