Protein Alignment Cyp313a4 and cyp46a1.3

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 507
• Identity: 136/507 - (26%)
• Similarity: 236/507 - (46%)
• Gaps: 89/507 - (17%)

  Fly     4 WTL--WCGLLF--LLWIYFLWSRRRFYLLTLK---IPGPLGYP----ILGMAHWLMR--REDIL- 54
            |.|  |..||.  |:.|.||......:.:.:|   ||||   |    .||.:..::|  :.::|
 Frog     4 WALIGWAALLLLALILICFLLFSGYIHYIHMKYDHIPGP---PRDSFFLGHSPTMLRLMKNNLLM 65

  Fly    55 -NAFGCFLDKHGPTI-FSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGV-----G 112
             :.|..::.|:||.: .:.|..:..::|| |:.|:::..||. .:|...|..:.:..||     |
 Frog    66 YDHFLGWVQKYGPVVRINGLHRVIILVVS-PEAVKELLMSPK-YSKDKFYDVIANMFGVRFMGKG 128

  Fly   113 LFSLKD-PRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQL-EPLQDDGEKDLIPLLQSFTL 175
            |.:.:| ..|...|::::|||....|:..:..||.:...|:::| |......|..:..:|...||
 Frog   129 LVTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDMLSRLTL 193

  Fly   176 GIATQTTMGSDVKDEESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAGKESHYYQAKTEI 240
            .:..:...|.::        |||       .:.:|....:..|..:...::......|..||
 Frog   194 DVIGKVAFGMEL--------NSL-------NDDLTPFPKAISLVMKGIVEMRNPMVRYSLAK--- 240

  Fly   241 RQFIRKI--------------IERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVED 291
            |.||||:              |||:..:.:.|         :.:.::::|.:::...     :|:
 Frog   241 RGFIRKVQESIRLLRQTGKECIERRQKQIQDG---------EEIPVDILTQILKGAA-----MEE 291

  Fly   292 E-------SNIIVF--GAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQ 347
            |       .|.:.|  ...|||||.:.:.:|.|...||..|:|..||..:..:..  |:.|.|..
 Frog   292 ECDPEILLDNFVTFFIAGQETTANQLSFVVMELGRNPEILEKAQAEIDEVIGSKR--DIEYEDLG 354

  Fly   348 QMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETF 412
            ::.||..:|.|::|:.|..|..||..::|:.: :|:.||:.|.|.::.|.|.|.::.:. |..||
 Frog   355 KLQYLSQVLKETLRLYPTAPGTSRGLTEDMVI-DGVKVPENVTIMLNSYIMGRMEQYYS-DPLTF 417

  Fly   413 NPDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFK 464
            |||.|.|.  ..|..|:|.||:.|.|:|||..::.:.|||.:||||:.|.|:
 Frog   418 NPDRFSPD--APKPYYSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYEFE 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	115/431 (27%)
cyp46a1.3	NP_001027517.1	CYP46A1-like	66..490	CDD:410706	117/442 (26%)