Protein Alignment Cyp313a4 and cyp46a1.1

DIOPT Version :9

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001018358.1
• Gene: cyp46a1.1 / 553543
• ZFINID: ZDB-GENE-050522-464
• Length: 501
• Species: Danio rerio
• Alignment Length: 521
• Identity: 125/521 - (23%)
• Similarity: 227/521 - (43%)
• Gaps: 74/521 - (14%)

  Fly     4 WTLWCGLLFLLWIYFLWSRRRFYLLTL-----KIPGPLGYP----ILGMAHWLMR-----REDIL 54
            |.|:.....|..::..:.....|:..|     .||||   |    :||.:..|.:     ...|.
Zfish     5 WVLYIVFFLLAAVFTAFLGYCLYIHHLHQKYDHIPGP---PRDSFLLGHSSSLTKAVYSDNNLIH 66

  Fly    55 NAFGCFLDKHGPTI-FSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDD-----GAGVGL 113
            :.|..:.:|:||.. .:.|..:..|:.. |:..:.|..||..:....:||.:.:     ..|.||
Zfish    67 DLFLHWAEKYGPVYRINTLHYVTIMVYC-PEATKTIMMSPKYIKDPFVYKQLFNLFGKRFLGNGL 130

  Fly   114 FSLKD-PRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLI-PLLQSFTLG 176
            .:..| ..|...|::::|||....|.|.:..|:..:..|:|:||.:.::....:: .|:...||.
Zfish   131 ITAVDHDMWYRQRRIMDPAFSSTYLRSLISTFDEMSERLMDKLEEMANNKTPAVMHDLVNCVTLD 195

  Fly   177 IATQTTMGSDVKDEESFRSNSLLGRYQCILETMTDMCFSPWL---NSRFCRQLAGKESHYYQAKT 238
            :..:...|.|:         :||.:.....:...::|....:   ...|.| |..|.....|...
Zfish   196 VICKVAFGVDL---------NLLNQKDSPFQNAVELCLKGMILDVRDPFFR-LFPKNWKLIQQVR 250

  Fly   239 EIRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVEDES---------- 293
            |..:.:||..|:.:...:...     .|.:::..:::|.:       ||:.|:|:
Zfish   251 EATELLRKTGEKWIQNRKTAV-----KNGEDVPKDILTQI-------LKSAEEENVNNTQDLEQM 303

  Fly   294 --NIIVF--GAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDL 354
              |.:.|  ...|||||.:.:.:|.|...||..:||..|:..:.....  ::|..|..::.||..
Zfish   304 LDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTKR--EISNEDLGKLTYLSQ 366

  Fly   355 ILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLP 419
            :|.|::|:.|..|..:|...:|:.: |||.||:|..:....|...|.:|.: .|...|:|:.|
Zfish   367 VLKETLRLYPTAPGTNRWLHEDIVI-NGIKVPRGCSVMFSSYVSQRLEKFF-KDPLKFDPERF-- 427

  Fly   420 HNIQDKHP-YAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDITMKLK 483
             ::....| |.|.||:.|.|.|:|..:|.:.||:.|||||:.:.| :..|.::....::.|::.|
Zfish   428 -DVNAPKPYYCYYPFSLGPRTCLGQVFAQMEAKLVLAKLLQRFEF-SLVPGQSFDIKDNGTLRPK 490

  Fly   484 S 484
            |
Zfish   491 S 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	p450	33..465	CDD:299894	115/466 (25%)
cyp46a1.1	NP_001018358.1	p450	39..495	CDD:278495	119/487 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010