DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a4 and Cyp4f40

DIOPT Version :9

Sequence 1:	NP_650224.3	Gene:	Cyp313a4 / 41563	FlyBaseID:	FBgn0038076	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_038935701.1	Gene:	Cyp4f40 / 503122	RGDID:	1559596	Length:	530	Species:	Rattus norvegicus

Alignment Length:	542	Identity:	138/542 - (25%)
Similarity:	214/542 - (39%)	Gaps:	138/542 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WCGL--------LFLLWIYFLWSRRR----FYLLTLKIPGPLGYPILGMAHWLMRREDILNAFGC 59
            |.||        |.|..:...|...|    .|.|..|.....|:|......|          |..
  Rat     8 WLGLGPMSASPWLLLSLVGVSWFLTRCLTQIYTLYAKCQRLCGFPQPPKRSW----------FWG 62

  Fly    60 FLDKHGPT-----------------IFSWLGPI-PFMIVSDPQVVQDIFTSPHCV--NKGIIYKA 104
            .|....||                 ..:||||| |.:.:..|.:::.:.::...|  ..||.|..
  Rat    63 HLGMSPPTEEGMKQMTELVATYPQGFMTWLGPIVPLITLCHPDIIRSVLSASAAVAPKDGIFYSF 127

  Fly   105 VDDGAGVGLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLIPL 169
            :....|.||......:||.||.:|.|||...:|..::.|||..|.::..:...|...|...|
  Rat   128 LKPWLGDGLLVSASDKWSRHRSMLTPAFHFNILKPYVKIFNDSTNIMHAKWLRLASGGSAHL--- 189

  Fly   170 LQSFTLGIATQTTMGSDVKDEESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAGKESHYY 234
                                 :.|.:.||:     .|:|:....||  .||. |::   |.|.|.
  Rat   190 ---------------------DMFENISLM-----TLDTLQKCVFS--FNSN-CQE---KPSEYI 222

  Fly   235 QAKTEIRQFIRK------------------------------------IIERKLAEDEMGALPSI 263
            .|..|:...:.|                                    |.||:....:.|....|
  Rat   223 AAILELSALVVKRNEQLLLHMDLLYRLTPDGRRFYKACHLVHDFTYAVIQERRRTLPKHGGDDVI 287

  Fly   264 QSNDKNLFLNLVTDLMRRGVFTLKNVED-----------ESNIIVFGAFETTANAVYYTLMLLAM 317
            ::..|:..|:.:      .|..|...||           |::..:|...:|||:.:.:.|..||.
  Rat   288 KAKAKSKTLDFI------DVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLAK 346

  Fly   318 FPEYQERAFEEIKTIFPNTGDFDVSYA-------DTQQMVYLDLILNESMRVIPPVPVVSRQTSQ 375
            .||||||..:|::.:..:....::..:       |..|:.:|.:.:.||:|:.|||.:|||..:|
  Rat   347 HPEYQERCRQEVQELLRDRDSEEIECSCGVLLRDDLAQLPFLTMCIKESLRLHPPVTMVSRCCTQ 411

  Fly   376 DLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKHPYAYIPFTKGIRNC 440
            |:.|.:|.|:|||:...|:|:..|.:..:| .|.|.::|..|.|.|||.:.|.|:|||:.|.|||
  Rat   412 DISLPDGRVIPKGIICIINIFATHHNPTVW-QDPEVYDPFRFDPENIQARSPLAFIPFSAGPRNC 475

  Fly   441 IGWRYALISAKVTLAKLLRNYR 462
            ||..:|:...||.:|..|..:|
  Rat   476 IGQTFAMNEMKVAVALTLLRFR 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	p450	33..465	CDD:299894	128/504 (25%)
Cyp4f40	XP_038935701.1	CYP4F	74..522	CDD:410772	121/466 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810