Protein Alignment Cyp313a4 and CYP4F3

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 131/504 - (25%)
• Similarity: 220/504 - (43%)
• Gaps: 78/504 - (15%)

  Fly     1 MLTWTLWCGLLFLLWIYFLWS---RRRFYLLTLKIPGP------LGYPILGMAH----WLMRRED 52
            :|....|.....|.|.|..:.   |.|.:      |.|      ||:  ||:.|    .|:..:.
Human    23 LLVGASWLLARILAWTYTFYDNCCRLRCF------PQPPKRNWFLGH--LGLIHSSEEGLLYTQS 79

  Fly    53 ILNAFG---CFLDKHGPTIFSWLGPIPFMI-VSDPQVVQDIFTSPHCV--NKGIIYKAVDDGAGV 111
            :...||   |:          |:||...:: :..|..::.:..:|..:  ...:.|..:....|.
Human    80 LACTFGDMCCW----------WVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGD 134

  Fly   112 GLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK--DLIPLLQSFT 174
            ||......:||.||::|.|||...:|..::.|||....::..:.:.|..:|..  |:...:...|
Human   135 GLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMT 199

  Fly   175 LGIATQTTMGSDVKDEES--------FRSNSLL-GRYQCILETMTDMCFSPWLNSRFCRQLAGKE 230
            |....:.....|...:|.        ...::|: .|:|.||           |...|...|....
Human   200 LDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL-----------LYIDFLYYLTPDG 253

  Fly   231 SHYYQAKTEIRQFIRKII-ERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVED--- 291
            ..:.:|...:..|...:| ||:......|....:|:..|:..|:.:      .|..|...||
Human   254 QRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFI------DVLLLSKDEDGKK 312

  Fly   292 --------ESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQ 348
                    |::..:|...:|||:.:.:.|..||..||||||..:|::.:..:....::.:.|..|
Human   313 LSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQ 377

  Fly   349 MVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFN 413
            :.:|.:.:.||:|:.||||.|||..:||:.|.:|.|:|||:...|.::..|.:..:| ||.|.::
Human   378 LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDPEVYD 441

  Fly   414 PDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYR 462
            |..|.|.||:::.|.|:|||:.|.|||||..:|:...||.|...|..:|
Human   442 PFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFR 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	113/424 (27%)
CYP4F3	NP_000887.2	CYP4F	74..515	CDD:410772	117/445 (26%)