Protein Alignment Cyp313a4 and cyp46a1.2

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_956755.3
• Gene: cyp46a1.2 / 393433
• ZFINID: ZDB-GENE-040426-1184
• Length: 501
• Species: Danio rerio
• Alignment Length: 528
• Identity: 125/528 - (23%)
• Similarity: 224/528 - (42%)
• Gaps: 99/528 - (18%)

  Fly    15 WIYFLWSRRRFYLLTL--------------------KIPGP------LGY-PILGMAHWLMRRED 52
            ||.::    .||||:.                    .||||      ||: |.|..|   |..:|
Zfish     5 WILYI----IFYLLSAVFTAFLAYCLYIHHLHQKYDHIPGPPRDNFLLGHSPSLTKA---MYSDD 62

  Fly    53 IL--NAFGCFLDKHGPTI-FSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDD-----GA 109
            .|  :.|..:.:::||.. .:.|..|. ::|..|:..:.|..||........|..:.:     ..
Zfish    63 SLIHDLFLQWAEQYGPVYRINTLHYIA-IVVHCPEATKTILMSPKYAKDPFSYSRLFNLFGKRFL 126

  Fly   110 GVGLFSLKD-PRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLI-PLLQS 172
            |.||.:..| ..|...|::::|||....|.|.:..|:..:..|:|:||.:.::....:: .|:..
Zfish   127 GNGLVTAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEMANNKTPAVMHDLVNC 191

  Fly   173 FTLGIATQTTMGSDVKDEESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAGKESHY--YQ 235
            .||.:..:...|.|:         :.|.:.....:...::|    ||.   ..|..::..:  :.
Zfish   192 VTLDVICKVAFGVDL---------NFLAQKDSPFQNAVELC----LNG---MALDARDPLFRIFP 240

  Fly   236 AKTEIRQFIR--KIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVEDES----- 293
            ...::.|.||  .::.||..|..:....:...|.:::..:::|.:       ||..|:|:
Zfish   241 KNWKLIQQIRDAAVLLRKTGEKWIQNRKTAVKNGEDVPKDILTQI-------LKIAEEENVNSSE 298

  Fly   294 -------NIIVF--GAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQM 349
                   |.:.|  ...|||||.:.:.:|.|...||..:||..|:..:.....  ::|..|..::
Zfish   299 DLEQMMDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTKR--EISNEDLGKL 361

  Fly   350 VYLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNP 414
            .||..:|.|::|:.|..|..:|...:|: :.|||.:|.|..:....:...|.:|.: .|...|:|
Zfish   362 TYLSQVLKETLRLYPTAPGTNRWLHEDM-IINGIKIPGGCSVMFSSFVSQRLEKFF-KDPLKFDP 424

  Fly   415 DHFLPHNIQDKHP---YAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVE 476
            :.|     .:..|   |.|.||..|.|.|:|..::.:.|||.|||||:.:.| :..|.::....:
Zfish   425 ERF-----DENAPKPYYCYYPFALGPRTCLGQVFSQMEAKVVLAKLLQRFEF-SLVPGQSFDIKD 483

  Fly   477 DITMKLKS 484
            ..|::.||
Zfish   484 TGTLRPKS 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	106/449 (24%)
cyp46a1.2	NP_956755.3	None