Protein Alignment Cyp313a4 and Cyp12b2

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 114/516 - (22%)
• Similarity: 192/516 - (37%)
• Gaps: 142/516 - (27%)

  Fly    32 IPGPLGYPILGMAH------WLMRREDI------LNAFGCFLDKHGPTIFSWLGPIPFMIVSDPQ 84
            |||.:|.|.....:      ...|.|.:      |.:...:...|.|.:|..:|
  Fly    96 IPGMMGKPNAVFTYNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVG----------- 149

  Fly    85 VVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLKDPRWSIHRKLLNPAFGHKVLLSF------LPI 143
                                       ||.|.:...|:..|..:||     ||:..      ||.
  Fly   150 ---------------------------GLASDQGQEWADIRNKVNP-----VLMKVQNVRQNLPQ 182

  Fly   144 FNRETALLLDQLE--------PLQDDGEKDL-IPLLQSFTLGIATQTTMG--SDVKDEESFRSNS 197
            .::.:...:|:||        .|..|....| :...:|.:. :|..|.||  ||..|..:.|
  Fly   183 LDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISF-VALNTRMGLLSDNPDPNADR--- 243

  Fly   198 LLGRYQCILETMTDMCFSPWLNSRF----------CRQLAG--KESHYYQAKTEIRQFIRKIIER 250
                   :.:.|.|     :.|..|          ..:.||  |....|...|:|.....:...|
  Fly   244 -------LAKHMRD-----FFNYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYIETAMR 296

  Fly   251 KLAEDEMG----ALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVEDESNIIVFGAFETTANAVYYT 311
            ...:::.|    .|..:..::|.:.:.:|.|::..|:                  :||::|....
  Fly   297 GFGKNDDGKTKCVLEQLLEHNKKVAVTMVMDMLMAGI------------------DTTSSACLTI 343

  Fly   312 LMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQD 376
            |..||..|..||:...|:..|.|.|.| .::..:|:.|.||...:.|.:|:....|...|.|.:|
  Fly   344 LYHLARNPSKQEKLRRELLRILPTTKD-SLTDQNTKNMPYLRACIKEGLRITSITPGNFRITPKD 407

  Fly   377 LKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNI----------QDKHPYAYI 431
            |.|| |..||:|..:.:.:..:....|.:...:| |.|:.:|..::          :.::|:.|:
  Fly   408 LVLS-GYQVPRGTGVLMGVLELSNDDKYFAQSSE-FIPERWLKSDLAPDIQACPAARTRNPFVYL 470

  Fly   432 PFTKGIRNCIGWRYALISAKVTLAKLLRNYRF----KTSFPFENLYFVE---DITMKLKSV 485
            ||..|.|.|||.|.|.:..:..|.:|||:|:.    :|...:|:...:.   ||..||:.|
  Fly   471 PFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIILSPCGDIRFKLEPV 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	105/471 (22%)
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	110/508 (22%)