Protein Alignment Cyp313a4 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 131/547 - (23%)
• Similarity: 225/547 - (41%)
• Gaps: 125/547 - (22%)

  Fly    10 LLFLLWIYF----LWSRRRFYLLTL-KIPGPLGYPILGMAHWLMRREDILNAFGCFLDKHGPTIF 69
            ||.|..:.|    .:.||::.|..| |.|..       .:|||...:        ..|:....:.
  Rat    24 LLSLFLVLFKAVQFYLRRQWLLKALEKFPST-------PSHWLWGHD--------LKDREFQQVL 73

  Fly    70 SWLGPIP------------FMIVSDPQVVQDI-------------FTSPHCVNKGIIYKAVDDGA 109
            :|:...|            .:::.||..|:.:             |.:|..|:          |.
  Rat    74 TWVEKFPGACLQWLSGSKTRVLLYDPDYVKVVLGRSDPKASGIYQFLAPWIVS----------GT 128

  Fly   110 GVGLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQD-DGEKDLIPLLQSF 173
            |.||..|...:|..|.::|.|||.:.:|..::.|.....:::||:.|.|.| |...::...:...
  Rat   129 GYGLLLLNGKKWFQHWRMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLM 193

  Fly   174 TL------GIATQTTMGSDVKD------------------EESFRSNSLLGRYQCILETMTDMCF 214
            ||      ..:.|.::..||..                  ..:|..||::          .:|..
  Rat   194 TLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLTFFRVRSAFYGNSII----------YNMSS 248

  Fly   215 SPWLNSRFCRQLAGKESHYYQAKTEIRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLM 279
            ...|:.|.|           |...|....:.|:.:.:|..:|     .:|...|...|:.:..|:
  Rat   249 DGRLSRRAC-----------QIAHEHTDGVIKMRKAQLQNEE-----ELQKARKKRHLDFLDILL 297

  Fly   280 RRGVFTLKNVEDES-----NIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGD- 338
            ...:...|::.||.     :..:|...:|||:.:.:....||..||:|||..||:::|.   ||
  Rat   298 FAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSIL---GDG 359

  Fly   339 FDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKK 403
            ..|::....|:.|..:.:.|::|:.||||.|||:.|..:...:|..:|||:...|.||.:|.:..
  Rat   360 TSVTWDHLDQISYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPS 424

  Fly   404 IWGPDAETFNPDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRF---KT 465
            .| |:.:.|:|..|.|.:  .:|.:||:||:.|.|||||.::|:...||.:|..|..:..   .|
  Rat   425 YW-PNPKVFDPSRFSPDS--PRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPT 486

  Fly   466 SFPFENLYFVEDITMKLKSVPLLELQK 492
            ..|..    :..:.:|.|:...|.|:|
  Rat   487 RIPVP----MARLVLKSKNGIHLRLKK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	114/482 (24%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	114/482 (24%)