Protein Alignment Cyp313a4 and CYP4V2

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_997235.3
• Gene: CYP4V2 / 285440
• HGNCID: 23198
• Length: 525
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 143/531 - (26%)
• Similarity: 256/531 - (48%)
• Gaps: 57/531 - (10%)

  Fly     6 LWCGLLF---LLW-------------IYFLWSRRRFYLLTLKIPGPL-----GYPILGMAHWLMR 49
            ||.||::   |||             :..|..|...|....:...|:     .||::|  |.|:.
Human     4 LWLGLVWQKLLLWGAASALSLAGASLVLSLLQRVASYARKWQQMRPIPTVARAYPLVG--HALLM 66

  Fly    50 REDILNAFGCFLD-----KHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGA 109
            :.|....|...::     :|.|.:..|:||:|.:.:.:.:.|:.|.||...::|..:||.::...
Human    67 KPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKFLEPWL 131

  Fly   110 GVGLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLIPLLQSFT 174
            |:||.:....:|...||:|.|.|...:|..||.|.|.:..:|:.:||...:....:....:....
Human   132 GLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCFFYITLCA 196

  Fly   175 LGIATQTTMGSDVKDEESFRSNSLLGRYQCILETMTDMCF----SPWLNSRFCRQLAGKESHYYQ 235
            |.|..:|.||.::..:.:..|..:...|:     |::|.|    .|||..... .|..||...::
Human   197 LDIICETAMGKNIGAQSNDDSEYVRAVYR-----MSEMIFRRIKMPWLWLDLW-YLMFKEGWEHK 255

  Fly   236 AKTEI-RQFIRKIIERKLAE---------DEMGALPSIQSNDKNLFLNL---VTDLMRRGVFTLK 287
            ...:| ..|...:|..:..|         |..|:.||  .|.:..||:|   ||| ......:.:
Human   256 KSLQILHTFTNSVIAERANEMNANEDCRGDGRGSAPS--KNKRRAFLDLLLSVTD-DEGNRLSHE 317

  Fly   288 NVEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYL 352
            ::.:|.:..:|...:|||.|:.::|.||...||.|::...|:..:| ...|...:..|.:::.||
Human   318 DIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVF-GKSDRPATVEDLKKLRYL 381

  Fly   353 DLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHF 417
            :.::.|::|:.|.||:.:|..|:|.::: |..|.||.:..|..|.:||..:.: |:.|.|.|:.|
Human   382 ECVIKETLRLFPSVPLFARSVSEDCEVA-GYRVLKGTEAVIIPYALHRDPRYF-PNPEEFQPERF 444

  Fly   418 LPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDITMKL 482
            .|.|.|.:|||||:||:.|.|||||.::|::..|..|:.:||::..:::...|.|.....:.::.
Human   445 FPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRP 509

  Fly   483 KSVPLLELQKR 493
            .:...::|::|
Human   510 SNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	122/440 (28%)
CYP4V2	NP_997235.3	CYP4V	76..515	CDD:410773	123/450 (27%)