Protein Alignment Cyp313a4 and Cyp3a2

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_063127162.1
• Gene: Cyp3a2 / 266682
• RGDID: 708379
• Length: 505
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 138/529 - (26%)
• Similarity: 236/529 - (44%)
• Gaps: 89/529 - (16%)

  Fly     3 TWTLWCGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMAHWLMRREDILNAF--------GC 59
            ||.|...:|.||  |.|.:.|........||||...|.||         .:||.:        .|
  Rat    11 TWVLLAVILVLL--YRLGTHRHGIFKKQGIPGPKPLPFLG---------TVLNYYKGLGRFDMEC 64

  Fly    60 FLDKHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHC----VNK------GIIYKAVDDGAGVGLF 114
            : .|:|.....:.|..|...:.|.::::::... .|    .|:      ||:.|||.
  Rat    65 Y-KKYGKIWGLFDGQTPVFAIMDTEMIKNVLVK-ECFSVFTNRRDFGPVGIMGKAVS-------- 119

  Fly   115 SLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK-DLIPLLQSFTLGIA 178
            ..||..|..:|.||:|.|....|....||..:...:|:..|:...:.|:. .:..:..::::.:.
  Rat   120 VAKDEEWKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTMKKVFGAYSMDVI 184

  Fly   179 TQTTMGSDV------KDEESFRSNSLLGRYQCILETMTDMCFSPWLNS-----RFCRQLAGKESH 232
            |.|:.|.:|      ||....::..|| |:.........:...|:|..     ..|  :..|:|.
  Rat   185 TSTSFGVNVDSLNNPKDPFVEKTKKLL-RFDFFDPLFLSVVLFPFLTPIYEMLNIC--MFPKDSI 246

  Fly   233 YYQAKTEIRQFIRKIIERKLAE-------DEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVE 290
            .:     .::|:.:|.|.:|..       |.:..:.:..:|.|:       ::..:   .|.:||
  Rat   247 AF-----FQKFVHRIKETRLDSKHKVHRVDFLQLMLNAHNNSKD-------EVSHK---ALSDVE 296

  Fly   291 --DESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLD 353
              .:|.|.:|..:|||::.:.:.|..||..|:.|::..|||....|:..  ..:|....:|.|||
  Rat   297 IIAQSVIFIFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKA--PPTYDIVMEMEYLD 359

  Fly   354 LILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFL 418
            ::|||::|:.|....:.|...:|::| :|:.:|||..:.|..|.:|...:.| |..|.|:|:.|.
  Rat   360 MVLNETLRLYPIGNRLERVCKKDIEL-DGLFIPKGSVVTIPTYALHHDPQHW-PKPEEFHPERFS 422

  Fly   419 PHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDITMKLK 483
            ..|.....||.|:||..|.|||||.|:||::.|:.|.|:|:|:.|:   |.:.    ..|.:||.
  Rat   423 KENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ---PCKE----TQIPLKLS 480

  Fly   484 SVPLLELQK 492
            ...:||.:|
  Rat   481 RQAILEPEK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	115/454 (25%)
Cyp3a2	XP_063127162.1	None