Protein Alignment Cyp313a4 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 137/532 - (25%)
• Similarity: 232/532 - (43%)
• Gaps: 98/532 - (18%)

  Fly     3 TWTLWCGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILG------MAHWLMRREDILNAFGCFL 61
            ||.|...:|.||  |...:|.........||||...|..|      |..|....|       |.
  Rat    11 TWVLLAVVLVLL--YGFGTRTHGLFKKQGIPGPKPLPFFGTVLNYYMGLWKFDVE-------CH- 65

  Fly    62 DKHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHC----VNK------GIIYKAVDDGAGVGLFSL 116
            .|:|.....:.|.:|...::|.::::::... .|    .|:      ||:.||:...
  Rat    66 KKYGKIWGLFDGQMPLFAITDTEMIKNVLVK-ECFSVFTNRRDFGPVGIMGKAISVS-------- 121

  Fly   117 KDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLIPLLQ---SFTLGIA 178
            ||..|..:|.||:|.|....|....|:..:...:|:..|.  |:.|:.  :|:.:   ::::.:.
  Rat   122 KDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLR--QEKGKP--VPVKEVFGAYSMDVI 182

  Fly   179 TQTTMGSDV------KDEESFRSNSLLG--------------RYQCILETMTDMCFSPWLNSRFC 223
            |.|:.|.:|      ||....::..||.              .:...:..|.::|..|
  Rat   183 TSTSFGVNVDSLNNPKDPFVEKAKKLLRIDFFDPLFLSVVLFPFLTPVYEMLNICMFP------- 240

  Fly   224 RQLAGKESHYYQAKTEIRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFT-LK 287
                 |:|         .:|.:|.:.| :.|..:.::...:.:...|.:|...|...:...| |.
  Rat   241 -----KDS---------IEFFKKFVYR-MKETRLDSVQKHRVDFLQLMMNAHNDSKDKESHTALS 290

  Fly   288 NVE--DESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMV 350
            ::|  .:|.|.:|..:|.|::.:.:.|..||..|:.|::..|||....||..  ..:|....:|.
  Rat   291 DMEITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKA--PPTYDTVMEME 353

  Fly   351 YLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPD 415
            |||::|||::|:.|....:.|...:|::: ||:.:|||..:.|..|.:||..:.| |:.|.|.|:
  Rat   354 YLDMVLNETLRLYPIGNRLERVCKKDVEI-NGVFMPKGSVVMIPSYALHRDPQHW-PEPEEFRPE 416

  Fly   416 HFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDITM 480
            .|...|.....||.|:||..|.|||||.|:||::.|:.|.|:|:|:.|:   |.:.    ..|.:
  Rat   417 RFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ---PCKE----TQIPL 474

  Fly   481 KLKSVPLLELQK 492
            ||....||:..|
  Rat   475 KLSRQGLLQPTK 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	116/459 (25%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	119/466 (26%)