Protein Alignment Cyp313a4 and Cyp4a2

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001038235.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 132/532 - (24%)
• Similarity: 228/532 - (42%)
• Gaps: 102/532 - (19%)

  Fly    10 LLFLLWIYF----LWSRRRFYLLTL-KIPGPLGYPILGMAHWLMRR-------EDILNAFGCFLD 62
            ||.|..:.|    .:.||::.|..| |.|..       .:|||...       :.:|.    :::
  Rat    24 LLSLFLVLFKAVQFYLRRQWLLKALEKFPST-------PSHWLWGHNLKDREFQQVLT----WVE 77

  Fly    63 KHGPTIFSWL-GPIPFMIVSDPQVVQDIF--TSPHCVNKGIIYKAVDDGAGVGLFSLKDPRWSIH 124
            |.......|| |....:::.||..|:.:.  :.|.      .|:::....|.||..|...:|..|
  Rat    78 KFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPK------PYQSLAPWIGYGLLLLNGKKWFQH 136

  Fly   125 RKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQD-DGEKDLIPLLQSFTL------GIATQTT 182
            |::|.|||.:.:|..::.|.....:::||:.|.|.| |...::...:...||      ..:.|.:
  Rat   137 RRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGS 201

  Fly   183 MGSDVKD------------------EESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAGK 229
            :..||..                  ..:|..||::          .:|.....|:.|.|
  Rat   202 VQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSII----------YNMSSDGRLSRRAC------ 250

  Fly   230 ESHYYQAKTEIRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVEDES- 293
                 |...|....:.|..:.:|..:|     .:|...|...|:.:..|:...:...|::.||.
  Rat   251 -----QIAHEHTDGVIKTRKAQLQNEE-----ELQKARKKRHLDFLDILLFAKMEDGKSLSDEDL 305

  Fly   294 ----NIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGD-FDVSYADTQQMVYLD 353
                :..:|...:|||:.:.:....||..||:|||..||:::|.   || ..|::....||.|..
  Rat   306 RAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSIL---GDGTSVTWDHLDQMPYTT 367

  Fly   354 LILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFL 418
            :.:.|::|:..|||.|||:.|..:...:|..:|||:::.|.||.:|.:...| |:.:.|:|..|.
  Rat   368 MCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYW-PNPKVFDPSRFS 431

  Fly   419 PHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRF---KTSFPFENLYFVEDITM 480
            |.:  .:|.:||:||:.|.|||||.::|:...||.:|..|..:..   .|..|..    :..:.:
  Rat   432 PDS--PRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVP----MPRLVL 490

  Fly   481 KLKSVPLLELQK 492
            |.|:...|.|:|
  Rat   491 KSKNGIHLRLKK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	114/460 (25%)
Cyp4a2	NP_001038235.1	CYP4B-like	69..499	CDD:410771	116/475 (24%)