Protein Alignment Cyp313a4 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 126/510 - (24%)
• Similarity: 221/510 - (43%)
• Gaps: 79/510 - (15%)

  Fly     2 LTWTLWCGLL-FLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMAHWLMRREDI-LNAFGCFLDKH 64
            :|::::.|:| :.|||:..|.|:       .:.||.|.|.:|:...|:..|.. |...|.:..|:
 Worm     9 VTFSIFLGILTYYLWIWTYWMRK-------GVKGPRGRPFVGVLDVLLEHETPGLIKLGEWTKKY 66

  Fly    65 GPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAG---------------VGLF 114
            |.......|....::|:||.:|.:||.           |..|:..|               |.|.
 Worm    67 GKVYGYTDGTQRTLVVADPAMVHEIFV-----------KQFDNFYGRKLNPIQGNPEKEQRVHLL 120

  Fly   115 SLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK-DLIPLLQSFTLGIA 178
            :.:..||...|.:.:.:|.:..|.............||..:|.....||: |::...|.:|:.:.
 Worm   121 AAQGYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQEYTMDVI 185

  Fly   179 TQTTMGSDVKDEESFRSNSLLGRYQCIL----ETMTDMC--FSPWLNSRFCRQLAGKESHYYQAK 237
            .:..||.  .|...|: |.::...:.|.    :.:..:|  |.|  ..:|.|.|..|.......|
 Worm   186 GRFAMGQ--TDSMMFK-NPIVNVVREIFCGSRKNLMLICQVFPP--IGQFIRDLTFKFPRIPAFK 245

  Fly   238 TEIRQFIRKIIERKLA--EDEMGALPSIQSNDKNLFLNLVTDLMRRGV-FTLKNVEDESN----- 294
              :...::.::..::|  |.|.||    :|.:...|::|..|.....| |:.:..||.|.
 Worm   246 --LYSIMQDVVAARIAQREREKGA----ESGEPQDFIDLFLDARSDDVDFSAEAREDFSKRNLKI 304

  Fly   295 --------------IIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYAD 345
                          :.:.|.|:|||.::.|...|||:.|:.||:..|||...|   |..:|.:..
 Worm   305 TKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREF---GTSEVEFEK 366

  Fly   346 TQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAE 410
            ..::.|:|.::.|::|:.|...:.:.:........||:.:..||.:.:|.:.:|...::||.|.:
 Worm   367 LGRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWGEDVK 431

  Fly   411 TFNPDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKT 465
            .|.|:.:......: |..||:||..|.|.|||.|.|::..|:.|..||:||.|:|
 Worm   432 EFKPERWSTDEPLE-HKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFET 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	108/445 (24%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	109/447 (24%)