Protein Alignment Cyp313a4 and cyp-13A11

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_499704.1
• Gene: cyp-13A11 / 184472
• WormBaseID: WBGene00008809
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 531
• Identity: 138/531 - (25%)
• Similarity: 224/531 - (42%)
• Gaps: 119/531 - (22%)

  Fly     3 TWTLW--CGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMAHWLMRREDILNAFGCFL---- 61
            |||.|  ||                      ||||.|||.||.|..:|..|:     ..||
 Worm    21 TWTYWRRCG----------------------IPGPQGYPFLGSALDMMDHEN-----PPFLQLKK 58

  Fly    62 --DKHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAG-------------- 110
              .::|.......|.:..:::||..::.::|.           |..|:..|
 Worm    59 WTSQYGKVYGITEGLLRTLVISDTNLIHEVFV-----------KQYDNFYGRNLNPIQGDPNREK 112

  Fly   111 -VGLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETAL-LLDQLEPLQDDGEK-DLIPLLQS 172
             |.|||.:..||...|.:.||.|....|.. :.:...::|| ||..:|.....|:. |::...|.
 Worm   113 RVTLFSAQGHRWKRLRTIANPTFSSNNLRK-IQVTVEDSALELLRHIEQHTAGGKAIDVLEYFQE 176

  Fly   173 FTLGIATQTTMGSDVKDEESFRSNSLL-------GRYQCILETMTDMCFSPWLNSRFCRQLAGKE 230
            ||:.:..:..||.  .|...|: |.||       |:.:..| .::.:.| ||:.     .:..|.
 Worm   177 FTMDVIGRIAMGQ--PDSLMFK-NPLLPCARDVFGKPRTAL-FLSGILF-PWIG-----PMIRKV 231

  Fly   231 SHYY---------QAKTEIRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLM------- 279
            ..|:         |...:....:.:.|::::||::.|..|....:..:|||:..:|.|
 Worm   232 VFYFTNVFNNPAAQIMYQTANAVEQRIKQRMAEEKAGIDPGEPQDFIDLFLDAKSDDMELENNED 296

  Fly   280 --RRGV-----FTLKNVEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTG 337
              :.||     .|...|..:..:.:...|:|||.::.|:..|||..|:.|::..|||..   ...
 Worm   297 FTKAGVKVTRQLTKDEVVGQCFVFLIAGFDTTALSLSYSSFLLATHPKAQKKLQEEIDR---ECA 358

  Fly   338 DFDVSYADTQQMVYLDLILNESMRVIPPVPVV-SRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRS 401
            |.:|::....::.|::.::.|::|:.|...:. ||:..:..|:.| ..:.|||.|..|.:.:|..
 Worm   359 DPEVTFDQLSKLKYMECVIKETLRMYPLGALANSRRCMRSTKIGN-YEIEKGVDILCDTWTLHYD 422

  Fly   402 KKIWGPDAETFNPDHFLPHNIQDKHPY---AYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRF 463
            |.|||.|||.|.|:.:   ...|:|.|   .||||..|.|.|||.|.|.:..|:.|:.:||.|..
 Worm   423 KSIWGEDAEEFKPERW---ESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTL 484

  Fly   464 ----KTSFPFE 470
                ||..|.:
 Worm   485 EVCNKTQIPLK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	118/461 (26%)
cyp-13A11	NP_499704.1	CYP3A-like	62..506	CDD:410678	118/463 (25%)