Protein Alignment Cyp313a4 and cyp-25A4

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_497779.1
• Gene: cyp-25A4 / 183248
• WormBaseID: WBGene00007967
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 126/514 - (24%)
• Similarity: 205/514 - (39%)
• Gaps: 134/514 - (26%)

  Fly    17 YFLWSRRRFYLL--TLKIPGPLGYPILGMAHWLMRR----EDILNAFGCFLD----------KHG 65
            |.:|.|...:.|  ::.||||   |:    |||...    :|.::..| :.|          |:|
 Worm    19 YSIWRRHAIFKLRSSIGIPGP---PV----HWLWGNLNIIKDRVSRLG-YNDTTQWHPTLHTKYG 75

  Fly    66 PTIFSWLGPIPFMIVSDPQVVQDIF----------TSP-----HCVNKGIIYKAVDDGAGVGLFS 115
            |....:.|....:.||:.:.:::||          .:|     :.:|:.::......|
 Worm    76 PIFGLYCGTQLHITVSEEEDIKEIFIQNFSNFSDRMTPDIFGMNQLNQSLLQNTYATG------- 133

  Fly   116 LKDPRWSIHRKLLNPAFG-------HKVLLSFLPIFNRETALLLDQLEPLQDDGEK-DLIPLLQS 172
                 |...|..:.|.|.       |:.|:|.:.||       |:.|:.....|:| |:....||
 Worm   134 -----WKHTRSAIAPIFSTGKMKAMHETLVSKIDIF-------LEVLKEKSSSGQKWDIFENFQS 186

  Fly   173 FTLGIATQTTMGSDVKDEESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAG----KESHY 233
            .:|.|..:.....|        ||....|        ||:.:..      .|:..|    |:|..
 Worm   187 LSLDIIGKCAFAID--------SNCQRDR--------TDLFYVQ------ARKFVGAVDLKKSWI 229

  Fly   234 YQAK------TEIRQFIRKIIERKLAEDEMGALPSIQ--------------SNDKNLFLNLVTDL 278
            ....      :.:.:|:.|..:...||     ||.::              .||....|||   |
 Worm   230 LPVSLILPELSWLWRFLYKFSDLSAAE-----LPLVKGLVDLYDRRRAGEGGNDSTDLLNL---L 286

  Fly   279 MRR---GVFTLKNVEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFD 340
            :||   |..|.:.|.:.....:...:|||:.|:.::..|||.:|..|::.:||||....|.|
 Worm   287 IRRETIGKMTQREVIENCFAFLIAGYETTSTAMMFSAYLLAEYPIVQQKLYEEIKKTKENAG--- 348

  Fly   341 VSYADTQQMVYLDLILNESMRVIPPVP-VVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKI 404
            ::|.....|.|||.:..||:|..||.. ..:|....|:.: .|.:.|:...:.:..|.:||:...
 Worm   349 LNYDSIHNMKYLDCVYKESLRFYPPTTHFTNRVCLNDMTI-RGQIYPEDSTLKVQPYTIHRNPAN 412

  Fly   405 W-GPDAETFNPDHFLPHNIQDK-HPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNY 461
            | .||  .|.|:.|  .|.::| ....:|||..|.|.|:|.|:|.:..|.|:||||..:
 Worm   413 WESPD--EFQPERF--ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTF 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	110/450 (24%)
cyp-25A4	NP_497779.1	CYP3A-like	73..494	CDD:410678	111/452 (25%)