Protein Alignment Cyp313a4 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 116/491 - (23%)
• Similarity: 203/491 - (41%)
• Gaps: 69/491 - (14%)

  Fly    11 LFLLWIYFLWSRRRFYLLTLKI----PGPLGYPILGMAHWLM--------RRE-----DILNAFG 58
            :|..:||.:.:||..:.|..||    |.|         ||.:        |:|     |....|.
 Worm    13 IFTFFIYIILARRERFKLREKIGLSGPEP---------HWFLGNLKQTAERKEKLGYDDANRWFN 68

  Fly    59 CFLDKHGPTIFSWLGPIPFMIVSDPQVVQDIFT------SPHCVNKGIIYKAVDDGAGVGLFSLK 117
            ...:::|.|...:.|....:::|:.:.::::|.      |...|..  ||:|....|.: |.:..
 Worm    69 ELHEQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPS--IYEANQLTASL-LMNSY 130

  Fly   118 DPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK-DLIPLLQSFTLGIATQT 181
            ...|...|..:.|.|....:.:.....|.:..|.||.|......|:| |:....|..||.:..:.
 Worm   131 SSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIGKC 195

  Fly   182 TMGSDVK-----------DEESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAGKESHYYQ 235
            ....|..           :.:.:.||..:...:.|..::    ..|.| |.|.:.|. |.:....
 Worm   196 AFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASV----LLPEL-STFWKALY-KYTPLAD 254

  Fly   236 AKTEIRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVEDESNIIVFGA 300
            |:..:.:.:..:.||:...:...::..::     |.||...|  :....|.:.|.:.....:...
 Worm   255 AEIPLVEGLSNVYERRRGGEGSDSVDLLK-----LLLNREDD--KSKPMTKQEVIENCFAFLLAG 312

  Fly   301 FETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPP 365
            :|||:.|:.|...||:.:|..|::.:|||.....|.|   ::|.....|.|||.:..|::|..||
 Worm   313 YETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKENGG---LTYDSIHNMKYLDCVYKETLRFYPP 374

  Fly   366 V-PVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDK-HPY 428
            | ..:.|...:|:.: .|...|||..:....:.:||:.:.| ...|.|:|:.|  .|.::| ...
 Worm   375 VIHFIRRLCREDITI-RGQFYPKGAIVVCLPHTVHRNPENW-DSPEEFHPERF--ENWEEKSSSL 435

  Fly   429 AYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFK 464
            .:|||..|.|.|:|.|:|.:..|.|:.|||..:..|
 Worm   436 KWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELK 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	100/420 (24%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	100/422 (24%)