Protein Alignment Cyp313a4 and cyp-25A2

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 501
• Identity: 108/501 - (21%)
• Similarity: 195/501 - (38%)
• Gaps: 87/501 - (17%)

  Fly    10 LLFLLWIYFLWSRRRFYLLTLKI----PGPLGYPILGMAHWLM--------RRE-----DILNAF 57
            ||....||.|::||..:.|..||    |.|         ||.|        |:|     |....|
 Worm    12 LLVSFIIYILFARREQFKLREKIGLTGPEP---------HWFMGNLKQIVDRKEKLGYDDSNKWF 67

  Fly    58 GCFLDKHGPTIFSWLGPIPFMIVSDPQVVQDIFT---------------SPHCVNKGIIYKAVDD 107
            .....::|.|...:.|....:::|:.:.::::|.               ..:.:|:.::......
 Worm    68 NELHKQYGETFGIYFGAQMNIVLSNEEDIKEVFIKNFSNFSDRIVPPIFDSNQLNQSLLQNTYAT 132

  Fly   108 GAGVGLFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEK-DLIPLLQ 171
            |            |...|..:.|.|....:.:.....:.:..|.||.|......|:| |:....|
 Worm   133 G------------WKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREKASSGQKWDIYEDFQ 185

  Fly   172 SFTLGIATQTTMGSDVK-----------DEESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQ 225
            ..||.:..:.....|..           :...|.:|..:...:.|..:......:|...:.:
 Worm   186 GLTLDVIGKCAFAIDSNCQRDRNDVFYVNARKFIANIDIRHSKVIAASFILPELAPLWRALY--- 247

  Fly   226 LAGKESHYYQAKTEIRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGVFTLKNVE 290
               |.:....|:..:.:.:..:.||:...:...::..::     |.||...|  :....|.:.|.
 Worm   248 ---KYTPLADAEIPLVEGLSNVYERRRGGEGSDSVDLLK-----LLLNREDD--KSKPMTKQEVI 302

  Fly   291 DESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLI 355
            :.....:...:|||:.|:.|...||:.:|..|::.:|||.....|.|   ::|.....|.|||.:
 Worm   303 ENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKENGG---LTYDSIHNMKYLDYV 364

  Fly   356 LNESMRVIPPV-PVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLP 419
            ..|::|..||| ..::|:...|:.: .|...|||..:....:.:|.:.:.| ...|.|:|:.|
 Worm   365 YKETLRCYPPVIHFINRRCLADITI-RGQFYPKGSVVTCLPHTVHLNPENW-DSPEEFHPERF-- 425

  Fly   420 HNIQDK-HPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFK 464
            .|.::| ....:|||..|.|.|:|.|:|.:..|.|:.|||..:..|
 Worm   426 ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELK 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	89/429 (21%)
cyp-25A2	NP_497776.2	CYP3A-like	73..495	CDD:410678	89/431 (21%)