Protein Alignment Cyp313a4 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_569092.2
• Gene: Cyp26a1 / 154985
• RGDID: 620161
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 527
• Identity: 134/527 - (25%)
• Similarity: 220/527 - (41%)
• Gaps: 106/527 - (20%)

  Fly    10 LLFL----LW-IYFLWSRRRFYLLTLKIPGPLGYPILG-MAHWLMRREDIL----NAFGCFLDKH 64
            ||||    || :|.:.||.|...|.|. ||.:|:|..| ....:::|...|    ..:|.....|
  Rat    19 LLFLAALKLWDLYCVSSRDRSCALPLP-PGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTH 82

  Fly    65 ---GPTIFSW---------LGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLK 117
               .||:...         ||....:.|..|..|:.|.                 |||. |.:|.
  Rat    83 LFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTIL-----------------GAGC-LSNLH 129

  Fly   118 DPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLI--PLLQSFTLGIATQ 180
            |......:|::..||..:.|..::|:...|.:..|:|   ....||:.|:  |.::.....||.:
  Rat   130 DSSHKQRKKVIMQAFNREALQCYVPVIAEEVSGCLEQ---WLSCGERGLLVYPEVKRLMFRIAMR 191

  Fly   181 TTMGSDV------KDE----ESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAG-KESHYY 234
            ..:|.:.      :||    |:|             |.||...||..::..|.....| |..:..
  Rat   192 ILLGCEPGPAGGGEDEQQLVEAF-------------EEMTRNLFSLPIDVPFSGLYRGVKARNLI 243

  Fly   235 QAKTE--IRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGV-FTLKNVEDESNII 296
            .|:.|  ||..||::   :.||.:.|...::|.        |:.....||. ..::.::..|..:
  Rat   244 HARIEENIRAKIRRL---QAAEPDAGCKDALQL--------LIEHSWERGERLDMQALKQSSTEL 297

  Fly   297 VFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKT---IFPNTGDFDVSYADTQQMVYLDLILNE 358
            :||..||||:|....:..|.::|...::..||||:   :..:..:..:.....:|:.|:..::.|
  Rat   298 LFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSHHEDKLDMETLEQLKYIGCVIKE 362

  Fly   359 SMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQ 423
            ::|:.||||...|...:..:| ||..:|||..:...|...|.....: .:.|.||||.|...:.:
  Rat   363 TLRLNPPVPGGFRVALKTFEL-NGYQIPKGWNVIYSICDTHDVADSF-TNKEEFNPDRFTSLHPE 425

  Fly   424 DKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNY---------RFKTS---FPFENL---- 472
            |...:::|||..|:|:|:|..:|.|..|:...:|.|..         ..|||   :|.:||
  Rat   426 DTSRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARRCDWQLLNGPPTMKTSPPVYPVDNLPARF 490

  Fly   473 -YFVEDI 478
             :|..||
  Rat   491 THFQGDI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	113/459 (25%)
Cyp26a1	NP_569092.2	cytochrome_P450	55..490	CDD:477761	115/481 (24%)