Protein Alignment Cyp313a4 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 527
• Identity: 139/527 - (26%)
• Similarity: 237/527 - (44%)
• Gaps: 86/527 - (16%)

  Fly     3 TWTLWCGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMAHWLMRREDILNAF--------GC 59
            ||.|....|.||:.|  .:|:........||||...|.||         .:||.:        .|
Mouse    11 TWVLLAISLVLLYRY--GTRKHELFKKQGIPGPKPLPFLG---------TVLNYYKGLWKFDMEC 64

  Fly    60 FLDKHGPTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFS-----LKDP 119
            : .|:|.|...:.|..|.:.|:||:.::::... .|.:   ::....|...||:.|     .||.
Mouse    65 Y-KKYGKTWGLFDGQTPLLAVTDPETIKNVLVK-ECFS---VFTNRRDFGPVGIMSKAISISKDD 124

  Fly   120 RWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGE----KDLIPLLQSFTLGIATQ 180
            .|..:|.||:|.|....|....|:..:...:|:..|......|:    ||   :|.::::.:.|.
Mouse   125 EWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKD---VLGAYSMDVITS 186

  Fly   181 TTMGSDV----KDEESF--RSNSLLGRYQCILETMTDMCFSPWLNS-----RFCRQLAGKESHYY 234
            |:.|.:|    ..|:.|  ::..|| |:......:..:...|:|..     ..|  :..|:|
Mouse   187 TSFGVNVDSLNNPEDPFVEKAKKLL-RFDFFDPLLFSVVLFPFLTPVYEMLNIC--MFPKDS--- 245

  Fly   235 QAKTEIRQFIRKIIERKLAEDEMGALPSIQSNDKNL--FLNLV-------TDLMRRGVFTLKNVE 290
                  .:|.:|.::| :.|..      :.|..|:.  ||.|:       .|.:.....:...:.
Mouse   246 ------IEFFKKFVDR-MKESR------LDSKQKHRVDFLQLMMNSHNNSKDKVSHKALSDMEIT 297

  Fly   291 DESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMVYLDLI 355
            .:|.|.:|..:|||::.:.:||..||..|:.|::..:||....||..  ..:|....:|.|||::
Mouse   298 AQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKA--PPTYDTVMEMEYLDMV 360

  Fly   356 LNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPH 420
            |||::|:.|....:.|...:|::| ||:.:|||..:.|..|.:|...:.|. :.|.|.|:.|...
Mouse   361 LNETLRLYPIANRLERVCKKDVEL-NGVYIPKGSTVMIPSYALHHDPQHWS-EPEEFQPERFSKE 423

  Fly   421 NIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDITMKLKSV 485
            |.....||.|:||..|.|||:|.|:||::.|:.|.|:::|:.|:   |.:.    ..|.:||...
Mouse   424 NKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQ---PCKE----TQIPLKLSRQ 481

  Fly   486 PLLELQK 492
            .||:.:|
Mouse   482 GLLQPEK 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	118/452 (26%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	121/459 (26%)