Protein Alignment Cyp313a4 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 527
• Identity: 135/527 - (25%)
• Similarity: 221/527 - (41%)
• Gaps: 106/527 - (20%)

  Fly    10 LLFL----LW-IYFLWSRRRFYLLTLKIPGPLGYPILG-MAHWLMRREDIL----NAFGCFLDKH 64
            ||||    || :|.:.||.|...|.|. ||.:|:|..| ....:::|...|    ..:|.....|
Mouse    19 LLFLAALKLWDLYCVSSRDRSCALPLP-PGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTH 82

  Fly    65 ---GPTIFSW---------LGPIPFMIVSDPQVVQDIFTSPHCVNKGIIYKAVDDGAGVGLFSLK 117
               .||:...         ||....:.|..|..|:.|.                 |||. |.:|.
Mouse    83 LFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTIL-----------------GAGC-LSNLH 129

  Fly   118 DPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLI--PLLQSFTLGIATQ 180
            |......:|::..||..:.|..::|:...|.:..|:|   ....||:.|:  |.::.....||.:
Mouse   130 DSSHKQRKKVIMQAFSREALQCYVPVIAEEVSSCLEQ---WLSCGERGLLVYPEVKRLMFRIAMR 191

  Fly   181 TTMGSDV------KDE----ESFRSNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAG-KESHYY 234
            ..:|.:.      :||    |:|             |.||...||..::..|.....| |..:..
Mouse   192 ILLGCEPGPAGGGEDEQQLVEAF-------------EEMTRNLFSLPIDVPFSGLYRGVKARNLI 243

  Fly   235 QAKTE--IRQFIRKIIERKLAEDEMGALPSIQSNDKNLFLNLVTDLMRRGV-FTLKNVEDESNII 296
            .|:.|  ||..||::   :..|.:.|...::|.        |:.....||. ..::.::..|..:
Mouse   244 HARIEENIRAKIRRL---QATEPDGGCKDALQL--------LIEHSWERGERLDMQALKQSSTEL 297

  Fly   297 VFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKT---IFPNTGDFDVSYADTQQMVYLDLILNE 358
            :||..||||:|....:..|.::|...::..||||:   :..:..|..:.....:|:.|...::.|
Mouse   298 LFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSNQDNKLDMETLEQLKYTGCVIKE 362

  Fly   359 SMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQ 423
            ::|:.||||...|...:..:| ||..:|||..:...|...|....|: .:.|.||||.|:..:.:
Mouse   363 TLRLNPPVPGGFRVALKTFEL-NGYQIPKGWNVIYSICDTHDVADIF-TNKEEFNPDRFIVPHPE 425

  Fly   424 DKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNY---------RFKTS---FPFENL---- 472
            |...:::|||..|:|:|:|..:|.|..|:...:|.|:.         ..|||   :|.:||
Mouse   426 DASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARF 490

  Fly   473 -YFVEDI 478
             :|..||
Mouse   491 THFQGDI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	CYP313-like	65..489	CDD:410680	114/459 (25%)
Cyp26a1	NP_031837.2	CYP26A1	55..490	CDD:410731	116/481 (24%)