Protein Alignment Cyp313a4 and CYP4F22

DIOPT Version :9

• Sequence 1: NP_650224.3
• Gene: Cyp313a4 / 41563
• FlyBaseID: FBgn0038076
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 143/534 - (26%)
• Similarity: 242/534 - (45%)
• Gaps: 87/534 - (16%)

  Fly     5 TLWCGLLFLLW---IYFLWSRRRFYLLTLKI---PGPLGYPILGMAHWLMRREDILNAFGCF--- 60
            ||...|||.|:   :.||...|.||:...::   |.|            .||..:|...|.:
Human    26 TLLLFLLFFLFRLLLRFLRLCRSFYITCRRLRCFPQP------------PRRNWLLGHLGMYLPN 78

  Fly    61 ----------LDKHGPTIFSWLGPI-PFMIVSDPQVVQDIFTSPHCV--NKGIIYKAVDDGAGVG 112
                      ||.....:..|:||: |.:::..|..::.:..:...:  ...:.|..:....|.|
Human    79 EAGLQDEKKVLDNMHHVLLVWMGPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDG 143

  Fly   113 LFSLKDPRWSIHRKLLNPAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLIPLLQSFTLGI 177
            |...|..:||.||:||.|||...:|..::.|||:...::..:...|. :|....:.:.:..:|
Human   144 LLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFNQSADIMHAKWRHLA-EGSAVSLDMFEHISL-- 205

  Fly   178 ATQTTMGSDVKDEESFRSN----------------SLLGRYQCILETMTDMCFSPWLNSRFCRQL 226
               .|:.|..|...|:.||                :|..|.|..|....|..:....:.|..||.
Human   206 ---MTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQA 267

  Fly   227 AGKESHYYQAKTEIRQFIRKIIERKLAEDEMGALPSIQSND-KNL-FLNLVTDLMRRG----VFT 285
            .....|:   .||:.|      ||:.|..:.||...:::.. |.| |::::  |:.|.    ..:
Human   268 CDMVHHF---TTEVIQ------ERRRALRQQGAEAWLKAKQGKTLDFIDVL--LLARDEDGKELS 321

  Fly   286 LKNVEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQERAFEEIKTIFPNTGDFDVSYADTQQMV 350
            .:::..|::..:|...:||::.:.:.|..||.:|||||:..|||:.:.......::.:.|..|:.
Human   322 DEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLP 386

  Fly   351 YLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGVQIAIDIYHMHRSKKIWGPDAETFNPD 415
            :..:.:.||:|..|||.:||||.::|:||.:|.::|||:...:.||..|.:..:| ||::.:||.
Human   387 FTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW-PDSKVYNPY 450

  Fly   416 HFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTLAKLLRNYRFKTSFPFENLYFVEDITM 480
            .|.|.|.|.:.|.||:||:.|.|||||..:|:...:|.:|..|..:|...           |.|.
Human   451 RFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSV-----------DRTR 504

  Fly   481 KLKSVPLLELQKRT 494
            |::..|  ||..||
Human   505 KVRRKP--ELILRT 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a4	NP_650224.3	p450	33..465	CDD:299894	124/469 (26%)
CYP4F22	NP_775754.2	p450	60..524	CDD:278495	132/500 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810