Protein Alignment mbo and nup88

DIOPT Version :10

• Sequence 1: NP_524330.2
• Gene: mbo / 41562
• FlyBaseID: FBgn0026207
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001016790.1
• Gene: nup88 / 549544
• XenbaseID: XB-GENE-1004636
• Length: 726
• Species: Xenopus tropicalis
• Alignment Length: 750
• Identity: 204/750 - (27%)
• Similarity: 360/750 - (48%)
• Gaps: 99/750 - (13%)

  Fly     9 LNKTELFAKIRNGLPVVQ--------RT------QNLLDCKDDLLFAWHAKDSCLLVRNWRS-SL 58
            |::..||::::.....|:        ||      :|||...|..|..|.:::...|....|| |:
 Frog    11 LSEHALFSRLKERTREVEELREEGERRTRKDKQLRNLLCVLDGDLLVWDSEECAFLTVRLRSLSV 75

  Fly    59 AAKVNIQFQTLIPSSLVSLEVDRVLASNEGSLVALSGPRGVVIMELPRRWGPDGYYKDGKPVITC 123
            .:..:...|.|:.::....||:.||.|.....|||.|.:||:::|:|:|||....::.|:..:.|
 Frog    76 ESTGSSGEQKLLCTNPPLFEVNEVLLSPTQHHVALVGSKGVMVLEIPKRWGKKSEFEGGEKTVNC 140

  Fly   124 RTFGLDTQLFLKNPHLEVRQVRWHPHSVSDSTLLVLLNNNTIRVYN-HSKLRHVWQVG------P 181
            |...:..::|..:..|.::|..|:|....:..|::|.::|.:|:|| |..|.....:.      .
 Frog   141 RAIPIAERIFTSSTSLVLKQALWYPSETQEPHLILLTSDNILRLYNLHDPLTPEKVISLSSAEEE 205

  Fly   182 PVLRSGANNSLCDFGELAVDFDIAPAAKPRVTEPETAGNNETTLDKSNKTLVAAKSLPKQERIEW 246
            ..|.....:.....||.||..|..|.               |.|.|      ......|::.:.:
 Frog   206 TTLPHNGRSYKASLGETAVACDFGPL---------------TPLPK------GFGQYNKEDTVAY 249

  Fly   247 PMVVLRENGNIYILMTGVDSENT---RLQGPVTITPQAHDNYGLESCALMIIPSLPPTIVIAESN 308
            |:.:|.|.|..|::...:...|.   :|.||:.:.|.|.||||.::||::.:..:|..||||..:
 Frog   250 PLYILYETGETYLMYIDLQKSNIKVGKLLGPLPMYPAAEDNYGYDACAVLCLACVPNIIVIATES 314

  Fly   309 GKLHHALLMEAE-----ATEHSFNEVDDSVLIEPAEYVVHVLETVELELGISAPATGKEGG---- 364
            |.|:|.:::|.|     .:..|:|...|.:   |:.|   |.|.|||||.:.. ||.:|..
 Frog   315 GLLYHCVVLEGEDDDEQTSNKSWNSSCDLI---PSLY---VFECVELELALKL-ATEEEESMELD 372

  Fly   365 -NCPIYLKRDLINELRYFAYHNAGLHAVTVSFIAELQRYLES-ESDEDRL-ELAVSAS--AEYIL 424
             :|||.|.||.|...||...|.||:|:|.:::..:|:::|.| |.|:|.| |||....  .|:||
 Frog   373 FSCPIKLHRDPICPSRYHCTHVAGVHSVGLAWFNKLEKFLGSGEEDKDSLQELAAEQKCLVEHIL 437

  Fly   425 CTKFDSSETVNAVFGLALLQIPAGIVLLLGSGQVISLKLVIDAQ-----LLVTPNENKP------ 478
            |||.......:.:.|..::.     .|.||:..:.   :..|.:     ||.|.....|
 Frog   438 CTKPLRCRLPSPIQGFWIIS-----DLSLGTSMIC---ITCDFECIARPLLTTIRPPSPPLLCFK 494

  Fly   479 VDSEVSQ------QESGPPFVDTIKSLLQRSVNQPIL---ADKLSSPSAQESFELLNQAIEVLRE 534
            :|...::      ::...||.:.|:.:|:|:...|:|   :.|.|||..:|..:||::|.:|.||
 Frog   495 IDKSSTEIIPHVLEDVKGPFEEHIRGILRRNSANPLLLNSSSKDSSPPPEECLQLLSRATQVFRE 559

  Fly   535 QYLKRHDLVRAAFTRHINQIQLKKEQQLQEIQDLEQERELISERAHKLAERFEEISYNQELLVRK 599
            :||.:.||.:....|.:..:.::||:||:::|..::||:.::|.|.:|||:|||....||.|:.:
 Frog   560 EYLLKQDLAKEEIQRRVKLLIVQKEKQLEDLQYCKEERKSLTEMAERLAEKFEEAKEKQEDLINR 624

  Fly   600 CNALMQRANASLPNSVIAEREFSQEVIRLNKVTQSLAAGLETAKKTFNKQRYHIAQSQEDLKKNA 664
            ...:::..|..||....:||:..:|:....:..|.|...:....:..:.|...:.:.:.. :|::
 Frog   625 LKRILRCFNTQLPVLSESERDMKKELHATQEQLQQLGNAINQVNRKMSYQEKQMEKGKSP-RKSS 688

  Fly   665 YELPEKQHRTITEILTQLTGEIDRQITDVKRINKI 699
            ..|.:.|.:.|..:|.: .||..:::  ||:||.:
 Frog   689 LTLSDYQKKNIKVVLKE-HGENIQEM--VKQINNV 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbo	NP_524330.2	Nup88	4..701	CDD:462975	204/749 (27%)
nup88	NP_001016790.1	Nup88	6..725	CDD:462975	204/749 (27%)