Protein Alignment mbo and nup88

DIOPT Version :9

• Sequence 1: NP_524330.2
• Gene: mbo / 41562
• FlyBaseID: FBgn0026207
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001018302.1
• Gene: nup88 / 321744
• ZFINID: ZDB-GENE-050522-297
• Length: 720
• Species: Danio rerio
• Alignment Length: 714
• Identity: 195/714 - (27%)
• Similarity: 342/714 - (47%)
• Gaps: 85/714 - (11%)

  Fly    29 QNLLDCKDDLLFAWHAKDSCLLVRNWR--SSLAAKVNIQFQTLIPSSLVSLEVDRVLASNEGSLV 91
            :||..|.:..||.|.:.:|.....|.|  :|.......::|||:..:....||..||.|.....|
Zfish    39 KNLTFCLNGDLFIWDSVESVFYTTNLRQLNSDGEPDTSRYQTLLCINPPLFEVCLVLVSPSQYHV 103

  Fly    92 ALSGPRGVVIMELPRRWGPDGYYKDGKPVITCRTFGLDTQLFLKNPHLEVRQVRWHPHSVSDSTL 156
            ||.|.||..::|||:|||....::.|:..|.|:|..:..:.|..:..:.:||..|:|....:..|
Zfish   104 ALIGQRGATVLELPQRWGKKSEFEGGRIQINCKTIPVAERFFTSSASVTLRQAVWYPSETEEPHL 168

  Fly   157 LVLLNNNTIRVYN------HSKLRHVWQV-GPPVLRSGANNSLCDFGELAVDFDIAPAA-KPRVT 213
            ::|.::||||.||      .:|:..|.|: ....:.:.:.:.....||.||.||..|.| .|.::
Zfish   169 VLLTSDNTIRFYNLKEPQSPAKVLSVSQLDDDSSVHTRSRSYAASLGETAVAFDFGPLADSPHLS 233

  Fly   214 EPETAGNNETTLDKSNKTLVAAKSLPKQERIEWPMVVLRENGNI---YILMTGVDSENTRLQGPV 275
            ....                      |.|.:.:|:.:|..||..   ||.::.......:..||:
Zfish   234 SLRM----------------------KAELVVYPLYILYGNGETFLNYISLSHSVGSLGKPMGPL 276

  Fly   276 TITPQAHDNYGLESCALMIIPSLPPTIVIAESNGKLHHALLMEAEATEHSFNEVDDSVLIE---- 336
            .:.|.|.||||.::||::.:|.:|..:|||..:|.|:|.:::|||       |.:|...:|
Zfish   277 PMYPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEAE-------EEEDGGAVERWSR 334

  Fly   337 -----PAEYVVHVLETVELELGISAPATGKE-----GGNCPIYLKRDLINELRYFAYHNAGLHAV 391
                 |:.|   |.|.|||||.:..||..:|     ...|||.|.||.:.:.||...|.||:|:|
Zfish   335 GSETAPSLY---VFECVELELTLKLPAGEEEEITESDFTCPIRLHRDPLCQHRYHCTHEAGVHSV 396

  Fly   392 TVSFIAELQRYLES-ESDEDRL-ELAVS--ASAEYILCTKFDSSETVNAVFGLAL---LQIPAGI 449
            .:::..:|.::||| |.|:|.| |||..  ...|:||||:..::.....|.|..:   |.:.|.:
Zfish   397 GLTWFKKLHKFLESDEEDKDSLQELAAEQRCIVEHILCTRPLANSLPAPVRGFWIVSDLSLGATM 461

  Fly   450 VLLLGSGQVISLKLVID----AQLLVTPNENKPVDSEVSQQESGPPFVDTIKSLLQRSVNQPIL- 509
            :.:..:.:.:.|.|:..    :..|:..:.....||...:..:...|...|:::|.||...|::
Zfish   462 ICITSTYECLLLPLLSSIRPASPPLLCSHPGAGSDSSPLRGLAEDSFEQHIRNILARSSTNPLML 526

  Fly   510 --ADKLSSPSAQESFELLNQAIEVLREQYLKRHDLVRAAFTRHINQIQLKKEQQLQEIQDLEQER 572
              .||.|||...|..:||::|.:|.||:|:.:..|......|.:..:..:|.:||:::....::|
Zfish   527 RSGDKDSSPPPSECLQLLSRATQVFREEYILKLGLAHEEMQRRVKLLSGQKNKQLEDLALCREDR 591

  Fly   573 ELISERAHKLAERFEEISYNQELLVRKCNALMQRANASLPNSVIAEREFSQEVIRLNKVTQSLAA 637
            :.::|.|.:||:::|:..|.||.::.:...::....:.||....:|::..:|:..:|...:.|..
Zfish   592 KSLTEAAERLADKYEDAKYRQEAIMNRVKRVLGSLRSQLPVLSDSEKDMRKELQTINDQLRHLDN 656

  Fly   638 GLE--TAKKTFNKQRYHIAQS--QEDLKKNAYELPEKQHRTITEILTQL---TGEIDRQITDVK 694
            |::  ..||.:.|::.:...|  ...|..||:     |.:.:..:|.:.   |..:.:||.|:|
Zfish   657 GIKQVNMKKDYQKKQMNAGASPAHSSLTLNAH-----QRKCLQGVLKEQGEHTAGMMKQIKDIK 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbo	NP_524330.2	Nup88	4..701	CDD:287177	195/714 (27%)
nup88	NP_001018302.1	Nup88	8..719	CDD:370849	195/714 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587194
Domainoid	1	1.000	238	1.000	Domainoid score	I2247
eggNOG	1	0.900	-	-		E1_KOG4460
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1901
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3341
OMA	1	1.010	-	-		QHG48720
OrthoDB	1	1.010	-	-		D1149034at2759
OrthoFinder	1	1.000	-	-		FOG0008173
OrthoInspector	1	1.000	-	-		oto41150
orthoMCL	1	0.900	-	-		OOG6_107382
Panther	1	1.100	-	-	LDO	PTHR13257
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4698
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800