Protein Alignment mbo and nup82

DIOPT Version :10

• Sequence 1: NP_524330.2
• Gene: mbo / 41562
• FlyBaseID: FBgn0026207
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_596415.2
• Gene: nup82 / 2539697
• PomBaseID: SPBC13A2.02
• Length: 798
• Species: Schizosaccharomyces pombe
• Alignment Length: 859
• Identity: 170/859 - (19%)
• Similarity: 302/859 - (35%)
• Gaps: 254/859 - (29%)

  Fly     1 MSLTDVLELNKT-----------ELFAK----IRNGLPV-VQRTQNLLDCKDDLLFAWHAKDSCL 49
            :|.||:||.:..           |:|.|    ..:.|.| |.:....|||:
pombe     5 VSWTDILEKHPALRWIKPIPEDWEIFPKHLCAFESFLYVAVGQEVRSLDCR-------------- 55

  Fly    50 LVRNWRSSLAAKVNIQFQTLIPSSLVSLEVDRVLASNEGSLVALSGPRGVVIMELPRRWGPDGYY 114
            |:::  .:.|:..|...:...|.  :...::::..|..|..:|:.|...:||:.|..:      .
pombe    56 LLKH--KNEASHKNFYKKLFNPE--LDFMIEQICLSKNGRFLAVVGKSKIVILGLRSK------L 110

  Fly   115 KDGKPVI-TCRTFGLDTQLF------------LK------------NPHLEVRQVRWHPHSVSDS 154
            .:..|:. :...||.....|            ||            ||..::..||:||...|..
pombe   111 SEQNPLAESVSNFGESVNNFSNSEHQENGTNSLKLSEVTICSVAVINPSSQIVSVRFHPLGKSGR 175

  Fly   155 TLLVLLNNNTIRVYNHSKLRHVWQVG----------PPVLRSGANNSLCDFGELAVD-------- 201
            :|:||...:.:          :::.|          |..|...|:||.    :..||
pombe   176 SLVVLTETSLL----------LYEAGNGVLMPDYEIPLKLTHQASNSF----DADVDLHIPTAFC 226

  Fly   202 ----------------------FDIAPAAKPRVTEPETA--------GNNETTLDKSNKTLVAAK 236
                                  |.:.|........|:..        ...|...|..|
pombe   227 FSNVSQGWGVFTIYILTRGGDVFSVCPVMPANAMIPQDVLKQIRLILTKKEDDADAEN------- 284

  Fly   237 SLPKQERIEWPMVVLRENGNIYILMTG-VDSENT----------------------RLQGPVTIT 278
               .:..:.|...:|.|......|.|. |.||.:                      .:|||..:.
pombe   285 ---HRRNVHWITKLLGEAALANDLSTSFVISEGSSELFDSSDYVSVRRPDDFSFIPSMQGPFLLQ 346

  Fly   279 PQAHDNYGLES-CALMIIPSLP-PTIVIAESNGKLHHALLMEAEATEHSFNEVDDSVLIEPAEYV 341
            |...|:..:|. |.:......| ..:.|..|.|:|.  ||:........:::::|..|.. .:.:
pombe   347 PAVADDELIEDYCDIYSFGMNPIDVLAIGGSEGRLD--LLLLVSEVSGRWSKLNDHGLAS-MKLI 408

  Fly   342 VHVLETVELELGISAPATGKEGGNCPIYLKRDLINELRYFAYHNAGLHAVTVSFIA-------EL 399
            |..:.::.|           ...|..:.|:.|:.:.....|||..|||.|.:...|       |.
pombe   409 VSQVHSLYL-----------SNNNPYMVLQPDIQSPYSLIAYHANGLHVVDIESWARDLNLNFEN 462

  Fly   400 QRYL--ESESDEDRL-ELAVSASAEYILCTKFDS---SETVNAVFGLALLQIPA-GIVLLLGSGQ 457
            ..:|  |.|:|||.| .:.||..:...:..:.|:   :|:.:||.|.|.|..|: |.:|
pombe   463 SEFLNNEEENDEDELSNVLVSIPSRTSVLERLDTNPLNESTDAVVGCAQLYYPSLGKIL------ 521

  Fly   458 VISL-----KLVIDAQLLVTPNENK-PVDSEVSQQES---------------------------G 489
             |||     ..|.|...|.|...|| .:.:|:...:|                           .
pombe   522 -ISLTRNWQTTVFDDSDLATMGVNKESLSNEMDYSKSLGTSSLEQVDDLDEKLTYTPLYVSLLEK 585

  Fly   490 PPFVD-TIKSLLQRSVNQPILADKLSSPSAQESFELLNQAIEVLREQYLKRHDLVRAAFTRHINQ 553
            .||.| :|.||::|::....|.::::..||  |...|.:.:...||..    :|:....:...::
pombe   586 TPFTDPSIPSLVERTIVPAELQNEITVSSA--SLRFLGKVVARYRETL----NLLDHGCSELHHR 644

  Fly   554 IQLKKEQ---QLQEIQDLEQERELISERAHKLAERFEEISYNQELLVRKCNALMQRA-NASLPNS 614
            ::|::|:   |...|..|........|:|.. .|..|.::.:..:..::.:.::||. :..:|:.
pombe   645 LKLQREEYERQQNHIYKLSDRISNFREKAWS-TEHLEHLTSDMSMCEKRIDQVLQRVMDLRVPDL 708

  Fly   615 VIAEREFSQEVIRL-NKVT--QSLAAGLETAKKTFNKQRYHIAQ-----SQEDLKKNAYELPEK- 670
            ...|::|.:|:... .|||  :.:...:||.|....:.:...||     |..|::..|.|..:|
pombe   709 SDKEKQFIKEIGNYKEKVTGERGIEKRVETLKTLLQRTKPRDAQTTLVASSSDMRLAAIEQLQKL 773

  Fly   671 ---QHRTITEILTQ 681
               |..:|.|:.|:
pombe   774 LAQQSLSIKELKTK 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mbo	NP_524330.2	Nup88	4..701	CDD:462975	169/856 (20%)
nup82	NP_596415.2	Nup88	<336..787	CDD:462975	106/478 (22%)