back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gnmt and GNMT

DIOPT Version :9

Sequence 1:	NP_650223.1	Gene:	Gnmt / 41561	FlyBaseID:	FBgn0038074	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_061833.1	Gene:	GNMT / 27232	HGNCID:	4415	Length:	295	Species:	Homo sapiens

Alignment Length:	291	Identity:	166/291 - (57%)
Similarity:	211/291 - (72%)	Gaps:	10/291 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DSVFVARSDGISAEGVRDQYADGKAAKVWEIFIGDKNSRTDNYKNFLIDMLRNKGCKRVLDVACG 70
            |||:..||.|::|||:.||||||:||:||:::|||..|||..||.:|:.:||..||:||||||||
Human     3 DSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACG 67

  Fly    71 TGVDSLMLVEEGFEVVSVDASDKMLKYALKERWARRNEAAFDKWVIEEANWLTLYDDIQEHIQDG 135
            |||||:|||||||.|.|||||||||||||||||.||:|.||||||||||||:||..|:.:..:.|
Human    68 TGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGG 132

  Fly   136 FDAVICLGNSFAHLMDGFGDQREHKQAIGNFEKCLKPGGVLLIDHRNYDNILETG-ATPAKSIYY 199
            ||||||||||||||.|..|||.||:.|:.|....::.||:|:|||||||:||.|| |.|.|:|||
Human   133 FDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYY 197

  Fly   200 NTSHTADIKTSVLFYCGKPALVSMDYLIA-------GNKLTSEFRLSYYPHGLKRFQEILAEIFS 257
            .:..|.|:.||||....|..:|::||.:.       |:...|:||||||||.|..|.|:|...|.
Human   198 KSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFTELLQAAFG 262

  Fly   258 AKAKHQLYGDFK--EMSQVKNPAFYIHLIEK 286
            .|.:|.:.||||  :..|...|.::||::::
Human   263 GKCQHSVLGDFKPYKPGQTYIPCYFIHVLKR 293

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.