Protein Alignment Dtg and RP1

DIOPT Version :9

• Sequence 1: NP_650220.2
• Gene: Dtg / 41558
• FlyBaseID: FBgn0038071
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_016869210.1
• Gene: RP1 / 6101
• HGNCID: 10263
• Length: 2163
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 99/513 - (19%)
• Similarity: 189/513 - (36%)
• Gaps: 137/513 - (26%)

  Fly    33 LLASCSAQPIESTSLPAEVDDVEGTTILPIQLEESSP-TPEPIIKNETATALPVVELKVAESNPV 96
            |.|:||...|:|....:|.:..:|.:.|......|.. .||..:...|.:...:..:..|.| |.
Human  1215 LSANCSTVNIQSVPKCSENERTQGISSLDGGCSASEACAPEVCVLEVTCSPCEMCTVNKAYS-PK 1278

  Fly    97 DPVEATDNFVSVYGGNLEQDIKNDVNSEVEDAPSPVEPIIEEVQKVAEAELENH---------EI 152
            :....:|.|....|..::|...|.. ..:.:..|..:.:..:   .|.|:.|||         |.
Human  1279 ETCNPSDTFFPSDGYGVDQTSMNKA-CFLGEVCSLTDTVFSD---KACAQKENHTYEGACPIDET 1339

  Fly   153 KLAVQSAREPKSLDAEEESKTIDEDRLENQDKAETVTDNIAVSSE--------QMESHIRPLPNV 209
            .:.|........|:::|.:.|.:.|..|..::.:.:..::.:.::        .:.|| :.:.|:
Human  1340 YVPVNVCNTIDFLNSKENTYTDNLDSTEELERGDDIQKDLNILTDPEYKNGFNTLVSH-QNVSNL 1403

  Fly   210 TSDLVSVILNEDKAITEQPITKTNLLALEQEHEKFEEIDESTTVPVYEEPKHQVTKKQGVEDPST 274
            :|  ..:.|:|.:|            .|:::|...::.:..:.....:|..:   ....:|:|.|
Human  1404 SS--CGLCLSEKEA------------ELDKKHSSLDDFENCSLRKFQDENAY---TSFDMEEPRT 1451

  Fly   275 VEIPPEVSDEQHFDPSEEPQTVRDERNLEEHDDNQNEINENIIEGEEAPAKTSTTAGPLVTVEPT 339
            .|.|..:::..    :...:.:.:..:.||.:::..:|...::.|.|               :.|
Human  1452 SEEPGSITNSM----TSSERNISELESFEELENHDTDIFNTVVNGGE---------------QAT 1497

  Fly   340 KSITEPNEEIEKKAE---AEAKAEMEEQ------VEV------NTPSVDATVVAADPDEAQDEVI 389
            :.:.:...|..|..|   ..:|..|||:      .|:      ..||:|....:....|.:
Human  1498 EELIQEEVEASKTLELIDISSKNIMEEKRMNGIIYEIISKRLATPPSLDFCYDSKQNSEKE---- 1558

  Fly   390 VAETTVEAITEAAKIVVEEEPKEDVSVQQEHLKEQRVQTVSESNRQASPTEEPIKEVIFPKGDDE 454
                |.|..|:..|::|               |.....:.|||    ||   .:|:.|      :
Human  1559 ----TNEGETKMVKMMV---------------KTMETGSYSES----SP---DLKKCI------K 1591

  Fly   455 SPVEGDSSESDEKPTERAIVDDDSSEEQNEDVVDEGKSSSDDSTATPLVSYPPHDAGQ 512
            |||..|  .||.:|        ||..||      ..|:||||          |:|:|:
Human  1592 SPVTSD--WSDYRP--------DSDSEQ------PYKTSSDD----------PNDSGE 1623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dtg	NP_650220.2	PTZ00341	<112..325	CDD:173534	35/229 (15%)
		rne	<303..445	CDD:236766	29/156 (19%)
		DUF3295	<410..>498	CDD:288540	24/87 (28%)
RP1	XP_016869210.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900