DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dtg and zormin

DIOPT Version :9

Sequence 1:NP_650220.2 Gene:Dtg / 41558 FlyBaseID:FBgn0038071 Length:612 Species:Drosophila melanogaster
Sequence 2:NP_001261317.1 Gene:zormin / 2769001 FlyBaseID:FBgn0052311 Length:3664 Species:Drosophila melanogaster


Alignment Length:734 Identity:154/734 - (20%)
Similarity:257/734 - (35%) Gaps:254/734 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 PIESTSLPAEVDDVEGTTILPIQLEESSPTPE-PIIKN------ETATALP------VVELK--- 89
            |..:|.|..::.| :|..:....:.:..|:|| .:.||      :..|.:.      .:|||   
  Fly  2142 PRFTTPLSGKIVD-QGADVSMEAIYDGFPSPEIKVEKNGGQLFEDAHTRISNKCNRVTIELKQVG 2205

  Fly    90 --------VAESNPVDPVEATDN-------FVSVYGGNLEQDI-----KNDVNSEVEDAPSPVEP 134
                    |..||.|....:|.:       |..|:|..|:..:     |..:..||...|.|...
  Fly  2206 VGDAGRYAVTASNTVGQSTSTADLVVKKTIFPPVFGRRLQAQVSKKGEKLTMEVEVTGLPEPTVT 2270

  Fly   135 IIEEVQKVAEAELENHEI-------KLAVQSAREP-------KSLDAEEESKTIDE--------D 177
            .:::.:.:.:|.:..|.:       :|.::.|:..       ::.:|..|:|:|.:        :
  Fly  2271 WLKDDKPLKDAGISEHRLLAQGNSYRLIIEKAQTTDSGKYMVRATNAGGEAKSIADCAILEPSPE 2335

  Fly   178 RLENQDKAETV---TDNIAVSSE---QMESHIRPLPN----------VTS--DLVSVILNEDKAI 224
            ||  |:..:|:   |..:|.:||   :::..|:...|          |||  ||..  |:|.|.|
  Fly  2336 RL--QEVVKTIVYETGPVAPASEFKTEVQKQIQNSENQQSYQNSQTEVTSANDLHG--LSESKVI 2396

  Fly   225 TEQPITKTNLLALEQEHEKFEEIDESTTVPVYEEPKHQV-----TKKQGVEDP------------ 272
            ||...|....:.||.: ..:.::.|.||.|........:     |....::.|            
  Fly  2397 TEHRCTTEATMRLEHK-SNYLDLPELTTRPKTPTTNDTITITTNTATVSMDQPDLTQPTITNTTT 2460

  Fly   273 -STVEIPPEVS------------DEQHFDPSEEPQTVRDER-NLEEHD--------DNQNEINEN 315
             :|.::||.|.            .:|...|   |||:...| ...||.        |...:|:|.
  Fly  2461 TNTTKVPPPVPPKPCTPVVATTFGQQQQQP---PQTLTSTRYEQSEHKSTTSSSSFDYFKKIDEE 2522

  Fly   316 IIEGEEAPAKTSTTAGPLVTVEPTKSITEPNEEIEKKAEAEAKAEMEEQVEVNTPSVDATVVAAD 380
            .|.....|    .|..||.||     :.:|          :|::..||...:|....||......
  Fly  2523 TIIQRPNP----LTFKPLDTV-----VRQP----------QAQSLAEELRSLNLIPGDAPEFCYS 2568

  Fly   381 PDEAQDEVIVAETTVEAITEAAKIVVEEEPKED---------------VSVQQEH--LKEQRVQ- 427
            |...:     :|..:..|||..||:.|.:|||.               .:||.|.  .||.:|: 
  Fly  2569 PKTER-----SEPKIPLITEKIKILSEVQPKEPPPQGGVPVFPPPLGLQTVQHESTTTKEVKVEY 2628

  Fly   428 ------------TVSESNRQASPTEEPIKEVI------FPKGDDESPVEGDSSESDEKPTERAIV 474
                        |.::.|.: ||:.:|..|.:      .|.|     |.|.:|:.::| :|:.::
  Fly  2629 GQPIVRPAAVLATPAQQNPR-SPSPKPSAEGVAMSRLWTPTG-----VTGYTSDVEQK-SEKTVI 2686

  Fly   475 DDDSSEEQNEDVVDEGKSSSDDSTATP--------LV-----SYPPHDAGQTFDSNSADEHSAQL 526
                               |..:|.||        ||     |.||..|..|...|         
  Fly  2687 -------------------SKLATPTPTKELNAPFLVNQIAKSIPPTTAPVTHLVN--------- 2723

  Fly   527 SGATNYRSTLIIALCSGTAVIFIVASLVIFVVSFQRQHGTLDIEMQEQRLGKD-IQEEDNV---Q 587
                       :.|..||      ...:.|....:.......:|..||:|.:: ||....|   .
  Fly  2724 -----------VELEPGT------PPEICFAPKVEETRRRSLVETMEQKLEQNLIQGPSKVLPHS 2771

  Fly   588 MKLLDVDLSSPV-ILPMGN 605
            :..|..:.::|| ..|:||
  Fly  2772 VPTLTPNTAAPVQPKPLGN 2790

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DtgNP_650220.2 PTZ00341 <112..325 CDD:173534 61/296 (21%)
rne <303..445 CDD:236766 41/179 (23%)
DUF3295 <410..>498 CDD:288540 23/123 (19%)
zorminNP_001261317.1 SPEC 126..332 CDD:238103
SPEC <504..641 CDD:295325
COG1340 960..1298 CDD:224259
RILP-like <1190..1315 CDD:304877
MAP7 1233..1365 CDD:283355
I-set 1390..1479 CDD:254352
IGc2 1403..1469 CDD:197706
I-set 1491..1580 CDD:254352
IGc2 1504..1570 CDD:197706
I-set 1589..1675 CDD:254352
Ig 1605..1675 CDD:299845
I-set 1702..1786 CDD:254352
Ig 1713..1786 CDD:299845
I-set 1811..1902 CDD:254352
Ig 1828..1892 CDD:143165
I-set 1927..2015 CDD:254352
IGc2 1940..2005 CDD:197706
I-set 2142..2231 CDD:254352 19/89 (21%)
Ig 2158..2231 CDD:299845 14/72 (19%)
I-set 2238..2325 CDD:254352 15/86 (17%)
Ig 2254..2324 CDD:299845 12/69 (17%)
I-set 3566..3655 CDD:254352
Ig 3583..3650 CDD:143165
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1181
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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