Protein Alignment Dtg and DMP1

DIOPT Version :9

• Sequence 1: NP_650220.2
• Gene: Dtg / 41558
• FlyBaseID: FBgn0038071
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_011530007.1
• Gene: DMP1 / 1758
• HGNCID: 2932
• Length: 542
• Species: Homo sapiens
• Alignment Length: 621
• Identity: 111/621 - (17%)
• Similarity: 219/621 - (35%)
• Gaps: 228/621 - (36%)

  Fly    68 SPTPEPIIKNETATALPVVELKVAESNPVDPVEA-----TDNFVSVY------------GGNLEQ 115
            :||| |:..:|::....|...:.|..:|.|..::     :|:...:|            ||:.:.
Human    69 APTP-PLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKD 132

  Fly   116 DIKNDVNSEV----EDAPSPVEPIIEEVQKVAEAELENHEIKLAVQSAREPKSLDAEEESKTIDE 176
            |.::|...:.    :..|.|     ::.|:...:.|.:.|              |:::..:..:|
Human   133 DDEDDSGDDTFGDDDSGPGP-----KDRQEGGNSRLGSDE--------------DSDDTIQASEE 178

  Fly   177 DRLENQDKAETVTDNIAVSSEQMESHIRPLPNVTSDLVSVILNEDKAITEQPITKTNLLALEQEH 241
            ...:.||.|:..|      ||..|                :.|||:              ::.:.
Human   179 SAPQGQDSAQDTT------SESRE----------------LDNEDR--------------VDSKP 207

  Fly   242 EKFEEIDESTTVPVYEEPKHQVTKKQGVEDPSTVEIPPEVSDEQHFDPSEEPQTVRDER------ 300
            |..:...||      |..:|.|  ..|.:..|:.....|:.||..  .|::|:::|.||
Human   208 EGGDSTQES------ESEEHWV--GGGSDGESSHGDGSELDDEGM--QSDDPESIRSERGNSRMN 262

  Fly   301 ------------------------NLEEH-------------DDNQNEINENIIEGEEAPAKTST 328
                                    .|.||             :|:::|:::|... ||..:.::.
Human   263 SAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTM-EEVKSDSTE 326

  Fly   329 TAGPLVTVEPTKSITEPNEEIEKKAEAEAKAEM--EEQVEVNTPSVDATVVA-----ADPDEAQD 386
            .:....|     .:::|..:.:..::.::|..:  ||...|:.||.:::..|     .:..|:|:
Human   327 NSNSRDT-----GLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQE 386

  Fly   387 EVIVAETTVEAITEAAKIVVEEE----PKEDVSVQQEHLKEQ--RVQTVSESNRQASPTEEPIKE 445
            || |:|:..:........|.::|    .:||.|....|.|.:  ..|..|||:...:.:||..:.
Human   387 EV-VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPES 450

  Fly   446 VIFPKGDDESPVEGDSSESDEKPTERAIVDDDSSEEQNEDVVDEGKSSSDDSTATPLVSYPPHDA 510
               |:.::.|..||..|.|....::.   ::..|||.:.|..|..: |.:||.:|
Human   451 ---PEDENSSSQEGLQSHSSSAESQS---EESHSEEDDSDSQDSSR-SKEDSNST---------- 498

  Fly   511 GQTFDSNSADEHSAQLSGATNYRSTLIIALCSGTAVIFIVASLVIFVVSFQRQHGTLDIEMQEQR 575
                :|.|:.|...||.                                        :||::.::
Human   499 ----ESKSSSEEDGQLK----------------------------------------NIEIESRK 519

  Fly   576 LGKDIQEEDNVQMKLLDVDLSSPVILPMGNEETDEC 611
            |..|.....                 |:|:::.::|
Human   520 LTVDAYHNK-----------------PIGDQDDNDC 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dtg	NP_650220.2	PTZ00341	<112..325	CDD:173534	43/259 (17%)
		rne	<303..445	CDD:236766	35/167 (21%)
		DUF3295	<410..>498	CDD:288540	24/89 (27%)
DMP1	XP_011530007.1	DMP1	30..542	CDD:284637	111/621 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900