DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6753 and lipf

DIOPT Version :9

Sequence 1:	NP_650219.2	Gene:	CG6753 / 41557	FlyBaseID:	FBgn0038070	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_998569.1	Gene:	lipf / 406713	ZFINID:	ZDB-GENE-040426-2737	Length:	396	Species:	Danio rerio

Alignment Length:	408	Identity:	134/408 - (32%)
Similarity:	219/408 - (53%)	Gaps:	42/408 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VLLCLALL--GLQQVSRATLRQSR-----EIIITDAVRRIQNDGYNVERHSVTTKDGYVLTLHRI 64
            ::|.|.:|  ||.|..::.|..:.     .:.|::.:|   :.||..|...|.|:|||:|:::||
Zfish     4 LVLSLVILTSGLVQYGQSALDGTGLDPEVNMNISEIIR---HWGYPAEEFEVVTEDGYILSINRI 65

  Fly    65 P----QVDPELGSLLRRPVVFLLSGLYASSDVWLLNGREDSLAYLLWRAGYDVWLGNNRGNIYCR 125
            |    ..:.|:     :|||||..||.|:...|:.|...:||.::|..||:|||:||:|||.:..
Zfish    66 PHGVKNKNEEV-----KPVVFLQHGLLAAGSNWVTNLPNNSLGFVLADAGFDVWIGNSRGNTWSC 125

  Fly   126 KNMWRNTTEREFWDFSWHEMGVYDLPAQVDYVLRTTGQKAMHFVGISQGGTVFLVLNSMMPQYNA 190
            |::..:..::|:|.||..||...||||.::::.:.|||:.:.:||.|||.|:..:..|.||:..:
Zfish   126 KHVSLDPRQKEYWKFSHDEMAKKDLPAVINFITKMTGQEQIFYVGHSQGTTIAFMAFSTMPELAS 190

  Fly   191 VFKSATLLAPVAYVSNTKSGLAK-------VIGPVLGTRNYVSKMLEGVEMFSTNKFFKKFLSMT 248
            ..|....|||||.|..|||.:.|       :|..:.|.:::          |..|:..|.|.:..
Zfish   191 KIKMFFALAPVATVGMTKSPMTKLSVIPEFLIWDLFGQKDF----------FPQNELIKFFATEF 245

  Fly   249 CLENEKPL--VCISRLWPAVGYDTRFLNKTLLPDLMANFPAGGSVKQLMHYFQGYVSTRFRQYDY 311
            |  :.|||  :|.:..:...|:|.:.||.:..|...|:.|||.||:.::|:.|...|::...|||
Zfish   246 C--SRKPLSVLCGNVFFLLCGFDEKNLNMSRTPVYTAHCPAGTSVQNMIHWAQAVKSSKLMAYDY 308

  Fly   312 GPERNWLHYQQLEPPEYALENVSTPVTVFFSENDYIVAPADIWRLLTRLPNVEAVYKVPWKRWNH 376
            |...|..||.|..||.|.::::..|..|:....|.:..|.|:..|||::|.:  |||...|.|.|
Zfish   309 GRAGNMAHYNQSTPPLYNIQDMMVPTAVWSGGQDTLADPKDVALLLTQIPKL--VYKRDIKHWEH 371

  Fly   377 FDFICGLGVREYIFDNIV 394
            .|||.|:...:.:::.::
Zfish   372 LDFIWGMDAPQEMYEKMI 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6753	NP_650219.2	PLN02872	39..394	CDD:215470	125/367 (34%)
lipf	NP_998569.1	PLN02872	4..393	CDD:215470	134/408 (33%)
		Abhydro_lipase	36..97	CDD:282003	24/68 (35%)
		Abhydrolase_5	78..242	CDD:289465	62/173 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574725
Domainoid	1	1.000	205	1.000	Domainoid score	I2877
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.860