DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6753 and CG31871

DIOPT Version :9

Sequence 1:	NP_650219.2	Gene:	CG6753 / 41557	FlyBaseID:	FBgn0038070	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	385	Identity:	147/385 - (38%)
Similarity:	222/385 - (57%)	Gaps:	13/385 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RQSREIIITDA----VRRIQNDGYNVERHSVTTKDGYVLTLHRIPQVDPELGSLLRRPVVFLLSG 85
            |..:..::.||    .:.|:..||..|.|:|.|||||:|.:||||:...:       ||: |:.|
  Fly    65 RNLKSDVLEDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRIPKKGAQ-------PVL-LMHG 121

  Fly    86 LYASSDVWLLNGREDSLAYLLWRAGYDVWLGNNRGNIYCRKNMWRNTTEREFWDFSWHEMGVYDL 150
            :..:|..|:|.|.:..|.|:|...|||||:||:|||.|.:.:...|:..:|||||::||||.|||
  Fly   122 ILDTSATWVLMGPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDL 186

  Fly   151 PAQVDYVLRTTGQKAMHFVGISQGGTVFLVLNSMMPQYNAVFKSATLLAPVAYVSNTKSGLAKVI 215
            ||.:||:|..||.:.:|::|.|||..:|.||.|..|.|.....|...|||:||:.:.||.|.:.:
  Fly   187 PANIDYILSKTGYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKSPLFRTL 251

  Fly   216 GPVLGTRNYVSKMLEGVEMFSTNKFFKKFLSMTCLENEKPL-VCISRLWPAVGYDTRFLNKTLLP 279
            ...|......::||...|.....||......:.|.:|.... ||.:.|:...||::..||||:||
  Fly   252 VLFLDFLTAATRMLRITEFMPNTKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLP 316

  Fly   280 DLMANFPAGGSVKQLMHYFQGYVSTRFRQYDYGPERNWLHYQQLEPPEYALENVSTPVTVFFSEN 344
            .::::.|:|.|:|||.|:.|...|..||::|.|..||.|.|.::.||:|.|..|..||.:::|.|
  Fly   317 VMLSHTPSGASIKQLEHFGQLMKSGHFRKFDRGYLRNQLEYNRMTPPDYDLSRVKVPVALYYSVN 381

  Fly   345 DYIVAPADIWRLLTRLPNVEAVYKVPWKRWNHFDFICGLGVREYIFDNIVLSMNRYEQRR 404
            |.:|:...:.||...||||...|.||.:|:||.||:..:.|:..:::.:|.::.|.|..|
  Fly   382 DLLVSTTGVDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVRNVRRVENHR 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6753	NP_650219.2	PLN02872	39..394	CDD:215470	140/355 (39%)
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	23/61 (38%)
		MhpC	93..436	CDD:223669	137/350 (39%)
		Abhydrolase_5	115..281	CDD:289465	68/166 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439456
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900