DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6753 and CG2772

DIOPT Version :9

Sequence 1:	NP_650219.2	Gene:	CG6753 / 41557	FlyBaseID:	FBgn0038070	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	158/383 - (41%)
Similarity:	213/383 - (55%)	Gaps:	21/383 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 AVRRIQNDGYNVERHSVTTKDGYVLTLHRIPQVDPELG-------SLLRRPVVFLLSGLYASSDV 92
            :..||...||..|.|.|.|.|||||.:.|||. .|:|.       |...||||.::.||::.||.
  Fly    35 SAERIAEHGYPAESHFVETPDGYVLNVFRIPH-SPKLNSNGNEGESEASRPVVLIMHGLFSCSDC 98

  Fly    93 WLLNGREDSLAYLLWRAGYDVWLGNNRGNIYCRKNMWRNTTEREFWDFSWHEMGVYDLPAQVDYV 157
            :||||.||:|.|....|||||||||.|||||.|.|...|.....||.|||||:|..||||.:||:
  Fly    99 FLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYI 163

  Fly   158 LRTTGQKAMHFVGISQGGTVFLVLNSMMPQYNAVFKSATLLAPVAYVSNTKSGLAKVIGPVLGTR 222
            |..|||:::|:||.|||.|.|.|:.|..|:|||..|:|.:|||..|:.|:..||.....|:.|..
  Fly   164 LAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHH 228

  Fly   223 NYVSKMLEGVEMFSTNKFFKKFLSMTCLENEKPLV---C--ISRLW--PAVGYDTRFLNKTLLPD 280
            ...|.:||...:...|.|.::.|..||  :.:|::   |  ::.||  |.:|.    ||:||||.
  Fly   229 GIGSTLLENQVLLPQNAFIQRVLDTTC--SNQPIMLSYCKTLAILWGGPEIGN----LNQTLLPQ 287

  Fly   281 LMANFPAGGSVKQLMHYFQGYVSTRFRQYDYGPERNWLHYQQLEPPEYALENVSTPVTVFFSEND 345
            :....|||.|..|.:||.|.|.|..||.||:|.:||..:|...|||.|.|..:::.:.:::...|
  Fly   288 IAETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKRNLEYYGVSEPPAYDLTKITSELYLYYGLAD 352

  Fly   346 YIVAPADIWRLLTRLPNVEAVYKVPWKRWNHFDFICGLGVREYIFDNIVLSMNRYEQR 403
            ......||.||...|||:..:::||...|.|.|||....|:..|.|.::.....|:.|
  Fly   353 GSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSKAYDAR 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6753	NP_650219.2	PLN02872	39..394	CDD:215470	155/368 (42%)
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	153/364 (42%)
		Abhydro_lipase	36..103	CDD:282003	29/67 (43%)
		Abhydrolase	113..>196	CDD:304388	47/82 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471680
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900