DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6753 and Lipm

DIOPT Version :9

Sequence 1:	NP_650219.2	Gene:	CG6753 / 41557	FlyBaseID:	FBgn0038070	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_220066.4	Gene:	Lipm / 309528	RGDID:	1304912	Length:	422	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	117/367 - (31%)
Similarity:	196/367 - (53%)	Gaps:	16/367 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 IQNDGYNVERHSVTTKDGYVLTLHRIPQVDPELGSLLRRPVVFLLSGLYASSDVWLLNGREDSLA 103
            |::.||..|.:.|.|:|||:|:::|||:...:|.....||||.|..||...:..|:.|...:||.
  Rat    53 IKHKGYPSEEYEVATEDGYILSVNRIPRGQTQLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLG 117

  Fly   104 YLLWRAGYDVWLGNNRGNIYCRKNMWRNTTEREFWDFSWHEMGVYDLPAQVDYVLRTTGQKAMHF 168
            ::|..||:|||:||:|||.:.||:...:..:.|||.||:.||..:||||.::::|:.||||.:::
  Rat   118 FILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKIYY 182

  Fly   169 VGISQGGTVFLVLNSMMPQYNAVFKSATLLAPVAYVSNTKS-GLAKVIGPVLGTRNYVSKMLEGV 232
            ||.|||.|:..:..|.||:.....|....|||:|.|.:.|| |...::.|        ..|::|:
  Rat   183 VGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKHAKSPGTKFLLLP--------DMMIKGL 239

  Fly   233 ----EMFSTNKFFKKFLSMTCLENEKPLVCISRLWPAVGYDTRFLNKTLLPDLMANFPAGGSVKQ 293
                |.....:||::.....|.:.....:|.:.:....|::|..:|.:.....:|:.|||.||:.
  Rat   240 FGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQN 304

  Fly   294 LMHYFQGYVSTRFRQYDYGPE-RNWLHYQQLEPPEYALENVSTPVTVFFSENDYIVAPADIWRLL 357
            ::|:.|...|...|.:|:|.| :|.....|..|..|.:.::..|..::....|::..|.|:..||
  Rat   305 ILHWSQAVNSGELRAFDWGSETKNREKSNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLL 369

  Fly   358 TRLPNVEAVYKVPWKRWNHFDFICGLGVREYIFDNIVLSMNR 399
            :.:.|:  :|......|.|.|||.||.....:::.|:..|.:
  Rat   370 SEVTNL--IYHKNIPEWAHVDFIWGLDAPHRVYNEIIHLMKQ 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6753	NP_650219.2	PLN02872	39..394	CDD:215470	115/360 (32%)
Lipm	XP_220066.4	Abhydro_lipase	49..111	CDD:282003	22/57 (39%)
		Abhydrolase_1	92..392	CDD:278959	98/309 (32%)
		Abhydrolase_5	93..>231	CDD:289465	56/137 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335448
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.910