DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6753 and Lipa

DIOPT Version :9

Sequence 1:	NP_650219.2	Gene:	CG6753 / 41557	FlyBaseID:	FBgn0038070	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_036864.3	Gene:	Lipa / 25055	RGDID:	3008	Length:	397	Species:	Rattus norvegicus

Alignment Length:	375	Identity:	124/375 - (33%)
Similarity:	197/375 - (52%)	Gaps:	28/375 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 IQNDGYNVERHSVTTKDGYVLTLHRIP-----QVD--PELGSLLRRPVVFLLSGLYASSDVWLLN 96
            |.:.||..|.|||.|.|||:|.:||||     |.|  |       :|||:|..|..|.|..|:.|
  Rat    39 IMHWGYPGEEHSVQTGDGYILGVHRIPHGRKNQFDKGP-------KPVVYLQHGFLADSSNWVTN 96

  Fly    97 GREDSLAYLLWRAGYDVWLGNNRGNIYCRKNMWRNTTEREFWDFSWHEMGVYDLPAQVDYVLRTT 161
            ...:||.::|..||:|||:||:|||.:.||:...:.::.|:|.||:.||..|||||.::|:|..|
  Rat    97 IDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEYWAFSFDEMAKYDLPASINYILNKT 161

  Fly   162 GQKAMHFVGISQGGTVFLVLNSMMPQYNAVFKSATLLAPVAYVSNTKSGLAKVIGPVLGTRNYVS 226
            ||:.:::||.|||.|:..:..|.||:.....|....||||.       .|....||::.......
  Rat   162 GQEQLYYVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPVL-------SLNFASGPMVKLGRLPD 219

  Fly   227 KMLE---GVEMFSTNKFFKKFLSM-TCLENEKPLVCISRLWPAVGYDTRFLNKTLLPDLMANFPA 287
            .:||   |.:.|.......|:||. .|.......:|.:..:...|::.:.||.:.:.....:.||
  Rat   220 LLLEDLFGQKQFLPQSAMVKWLSTHICTHVIMKELCANIFFLICGFNEKNLNMSRVDVYTTHCPA 284

  Fly   288 GGSVKQLMHYFQGYVSTRFRQYDYG-PERNWLHYQQLEPPEYALENVSTPVTVFFSENDYIVAPA 351
            |.||:.::|:.|.....:.:.:|:| .::|:.||.|..||.|:::::..|..::....|::...:
  Rat   285 GTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLYSIKDMQLPTALWSGGKDWLADTS 349

  Fly   352 DIWRLLTRLPNVEAVYKVPWKRWNHFDFICGLGVREYIFDNIVLSMNRYE 401
            ||..|||.:|.:  ||......|:|.|||.||.....:::.:|..|.:|:
  Rat   350 DINILLTEIPTL--VYHKNIPEWDHLDFIWGLDAPWRLYNEVVSLMKKYQ 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6753	NP_650219.2	PLN02872	39..394	CDD:215470	121/366 (33%)
Lipa	NP_036864.3	PLN02872	7..394	CDD:215470	122/370 (33%)
		Abhydro_lipase	35..96	CDD:282003	27/63 (43%)
		Abhydrolase_5	78..>203	CDD:289465	54/131 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335492
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.910