Protein Alignment CG11600 and LIPF

DIOPT Version :9

• Sequence 1: NP_650217.2
• Gene: CG11600 / 41555
• FlyBaseID: FBgn0038068
• Length: 406
• Species: Drosophila melanogaster
• Sequence 2: NP_001185758.1
• Gene: LIPF / 8513
• HGNCID: 6622
• Length: 408
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 127/422 - (30%)
• Similarity: 205/422 - (48%)
• Gaps: 65/422 - (15%)

  Fly    12 WLLIV-------------------SGMPKVKFGLQNFTGRGKDYRIKVITGILIIDKYGYSVETH 57
            |||:.                   .|.|:|...:..                 :|..:||..|.:
Human    12 WLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQ-----------------MITYWGYPNEEY 59

  Fly    58 TVRTGDGYILDMFRIP-SSPNCKEDGFKPSVLIQHGLISLADSFLVTGPRSGLPFMLADRCYDVW 121
            .|.|.|||||::.||| ...|....|.:|.|.:||||::.|.:::...|.:.|.|:|||..||||
Human    60 EVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVW 124

  Fly   122 LSNSRGVRYSQRHIRLKASQDAFWRFSWHEMGMEDLPAMIDYILSTTNEEALHFVCHSQGCTTLL 186
            |.||||..:::|::........||.||:.||...||||.||:|:..|.::.||:|.||||.|...
Human   125 LGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGF 189

  Fly   187 VLLSMKPEYNRMIKTANMMAPAVFMKHARNKLMKM-----------FGNIIMSMKDSSFFGPLDA 240
            :..|..|...:.|||...:||...:|:.::.:.|:           ||:.|  ....:||.
Human   190 IAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKI--FYPHNFFD---- 248

  Fly   241 IRFLLSVFCKCSKFKKLCA-FMFILASEEPTSYMNNTAIPLILATHPGAISTRQPKHFLQLRKSG 304
             :||.:..|.......||: .:||:...:..:: |.:.:.:.|:.:|...|.:...|:.|..|||
Human   249 -QFLATEVCSREMLNLLCSNALFIICGFDSKNF-NTSRLDVYLSHNPAGTSVQNMFHWTQAVKSG 311

  Fly   305 KFRPYDFG-VMRNKKLYNQDTPPDYPLENVRPQS-PIHIYHSHGDDLVARKDIHILISKLDKAVL 367
            ||:.||:| .::|:..|:|..||.|   ||...: ||.:::...|.|...:|:.:|:.||...:.
Human   312 KFQAYDWGSPVQNRMHYDQSQPPYY---NVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPNLIY 373

  Fly   368 H-DVVFEKWSHSDFLFAKLIKKVVNEPIIKVI 398
            | ::.|  ::|.||::|....:.|...|:.:|
Human   374 HKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11600	NP_650217.2	PLN02872	46..396	CDD:215470	120/365 (33%)
		Abhydro_lipase	46..104	CDD:282003	23/58 (40%)
LIPF	NP_001185758.1	PLN02872	14..400	CDD:215470	123/415 (30%)
		Abhydro_lipase	45..107	CDD:282003	23/78 (29%)
		Abhydrolase_5	88..>211	CDD:289465	51/122 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.860